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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PAK7
All Species:
25.76
Human Site:
Y146
Identified Species:
40.48
UniProt:
Q9P286
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P286
NP_065074.1
719
80745
Y146
A
D
Y
T
T
E
K
Y
R
E
K
S
L
Y
G
Chimpanzee
Pan troglodytes
XP_525261
777
87548
Y204
A
D
Y
T
T
E
K
Y
R
E
K
S
L
Y
G
Rhesus Macaque
Macaca mulatta
XP_001113709
777
87522
Y204
A
D
Y
T
T
E
K
Y
R
E
K
S
L
Y
G
Dog
Lupus familis
XP_542895
719
81009
Y146
A
D
Y
T
T
E
K
Y
R
E
K
S
L
Y
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8C015
719
80930
Y146
A
D
Y
T
T
E
K
Y
R
D
R
S
L
Y
G
Rat
Rattus norvegicus
P35465
544
60559
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514843
722
81837
Y146
A
D
Y
V
S
D
K
Y
R
D
R
S
F
Y
G
Chicken
Gallus gallus
XP_415031
787
88575
Y210
T
D
Y
V
M
D
K
Y
R
D
K
T
L
Y
G
Frog
Xenopus laevis
NP_001082100
650
73749
R102
C
R
S
N
S
L
R
R
E
S
P
P
C
Q
P
Zebra Danio
Brachydanio rerio
NP_998127
711
78596
R146
E
W
Q
R
S
S
L
R
Q
N
G
H
P
G
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VXE5
639
69601
N91
K
A
D
T
T
S
L
N
S
S
S
T
M
M
M
Honey Bee
Apis mellifera
XP_001122147
624
70155
V76
I
L
D
L
K
T
I
V
R
G
H
N
D
P
K
Nematode Worm
Caenorhab. elegans
Q17850
572
63863
R24
R
F
S
S
S
A
T
R
E
N
Q
V
V
G
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03497
939
102344
D316
I
K
R
N
S
Q
D
D
K
R
A
S
S
S
S
Red Bread Mold
Neurospora crassa
Q7RZD3
954
103773
E361
Q
F
T
G
L
P
K
E
W
Q
R
L
I
S
E
Conservation
Percent
Protein Identity:
100
92.2
91.8
96.9
N.A.
93.8
31.2
N.A.
85.8
75.7
53.1
64.9
N.A.
45.6
45.4
31.1
N.A.
Protein Similarity:
100
92.4
92.2
98.3
N.A.
96.8
48.6
N.A.
92.5
82
64.8
75
N.A.
58.2
61
47
N.A.
P-Site Identity:
100
100
100
100
N.A.
86.6
0
N.A.
60
60
0
0
N.A.
13.3
6.6
0
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
0
N.A.
86.6
80
13.3
13.3
N.A.
26.6
13.3
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27
27.7
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.2
42.6
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
40
7
0
0
0
7
0
0
0
0
7
0
0
0
0
% A
% Cys:
7
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% C
% Asp:
0
47
14
0
0
14
7
7
0
20
0
0
7
0
0
% D
% Glu:
7
0
0
0
0
34
0
7
14
27
0
0
0
0
7
% E
% Phe:
0
14
0
0
0
0
0
0
0
0
0
0
7
0
0
% F
% Gly:
0
0
0
7
0
0
0
0
0
7
7
0
0
14
47
% G
% His:
0
0
0
0
0
0
0
0
0
0
7
7
0
0
0
% H
% Ile:
14
0
0
0
0
0
7
0
0
0
0
0
7
0
0
% I
% Lys:
7
7
0
0
7
0
54
0
7
0
34
0
0
0
7
% K
% Leu:
0
7
0
7
7
7
14
0
0
0
0
7
40
0
14
% L
% Met:
0
0
0
0
7
0
0
0
0
0
0
0
7
7
7
% M
% Asn:
0
0
0
14
0
0
0
7
0
14
0
7
0
0
0
% N
% Pro:
0
0
0
0
0
7
0
0
0
0
7
7
7
7
7
% P
% Gln:
7
0
7
0
0
7
0
0
7
7
7
0
0
7
0
% Q
% Arg:
7
7
7
7
0
0
7
20
54
7
20
0
0
0
0
% R
% Ser:
0
0
14
7
34
14
0
0
7
14
7
47
7
14
7
% S
% Thr:
7
0
7
40
40
7
7
0
0
0
0
14
0
0
0
% T
% Val:
0
0
0
14
0
0
0
7
0
0
0
7
7
0
0
% V
% Trp:
0
7
0
0
0
0
0
0
7
0
0
0
0
0
0
% W
% Tyr:
0
0
47
0
0
0
0
47
0
0
0
0
0
47
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _