KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PAK7
All Species:
28.48
Human Site:
Y152
Identified Species:
44.76
UniProt:
Q9P286
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P286
NP_065074.1
719
80745
Y152
K
Y
R
E
K
S
L
Y
G
D
D
L
D
P
Y
Chimpanzee
Pan troglodytes
XP_525261
777
87548
Y210
K
Y
R
E
K
S
L
Y
G
D
D
L
D
P
Y
Rhesus Macaque
Macaca mulatta
XP_001113709
777
87522
Y210
K
Y
R
E
K
S
L
Y
G
D
D
L
D
P
Y
Dog
Lupus familis
XP_542895
719
81009
Y152
K
Y
R
E
K
S
L
Y
G
D
D
L
D
P
F
Cat
Felis silvestris
Mouse
Mus musculus
Q8C015
719
80930
Y152
K
Y
R
D
R
S
L
Y
G
D
D
L
D
L
Y
Rat
Rattus norvegicus
P35465
544
60559
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514843
722
81837
Y152
K
Y
R
D
R
S
F
Y
G
E
E
L
D
R
C
Chicken
Gallus gallus
XP_415031
787
88575
Y216
K
Y
R
D
K
T
L
Y
G
E
E
L
D
R
Y
Frog
Xenopus laevis
NP_001082100
650
73749
Q108
R
R
E
S
P
P
C
Q
P
R
E
D
R
F
H
Zebra Danio
Brachydanio rerio
NP_998127
711
78596
G152
L
R
Q
N
G
H
P
G
L
G
P
G
P
I
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VXE5
639
69601
M97
L
N
S
S
S
T
M
M
M
G
S
M
A
P
M
Honey Bee
Apis mellifera
XP_001122147
624
70155
P82
I
V
R
G
H
N
D
P
K
G
R
T
F
S
G
Nematode Worm
Caenorhab. elegans
Q17850
572
63863
G30
T
R
E
N
Q
V
V
G
L
K
P
L
P
K
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03497
939
102344
S322
D
D
K
R
A
S
S
S
S
N
N
S
S
S
S
Red Bread Mold
Neurospora crassa
Q7RZD3
954
103773
S367
K
E
W
Q
R
L
I
S
E
S
G
I
T
E
K
Conservation
Percent
Protein Identity:
100
92.2
91.8
96.9
N.A.
93.8
31.2
N.A.
85.8
75.7
53.1
64.9
N.A.
45.6
45.4
31.1
N.A.
Protein Similarity:
100
92.4
92.2
98.3
N.A.
96.8
48.6
N.A.
92.5
82
64.8
75
N.A.
58.2
61
47
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
80
0
N.A.
53.3
66.6
0
0
N.A.
6.6
6.6
6.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
0
N.A.
80
93.3
20
6.6
N.A.
26.6
13.3
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27
27.7
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.2
42.6
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
7
0
0
0
0
0
0
0
7
0
0
% A
% Cys:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
7
% C
% Asp:
7
7
0
20
0
0
7
0
0
34
34
7
47
0
0
% D
% Glu:
0
7
14
27
0
0
0
0
7
14
20
0
0
7
7
% E
% Phe:
0
0
0
0
0
0
7
0
0
0
0
0
7
7
7
% F
% Gly:
0
0
0
7
7
0
0
14
47
20
7
7
0
0
7
% G
% His:
0
0
0
0
7
7
0
0
0
0
0
0
0
0
7
% H
% Ile:
7
0
0
0
0
0
7
0
0
0
0
7
0
7
0
% I
% Lys:
54
0
7
0
34
0
0
0
7
7
0
0
0
7
7
% K
% Leu:
14
0
0
0
0
7
40
0
14
0
0
54
0
7
0
% L
% Met:
0
0
0
0
0
0
7
7
7
0
0
7
0
0
7
% M
% Asn:
0
7
0
14
0
7
0
0
0
7
7
0
0
0
0
% N
% Pro:
0
0
0
0
7
7
7
7
7
0
14
0
14
34
0
% P
% Gln:
0
0
7
7
7
0
0
7
0
0
0
0
0
0
0
% Q
% Arg:
7
20
54
7
20
0
0
0
0
7
7
0
7
14
7
% R
% Ser:
0
0
7
14
7
47
7
14
7
7
7
7
7
14
7
% S
% Thr:
7
0
0
0
0
14
0
0
0
0
0
7
7
0
0
% T
% Val:
0
7
0
0
0
7
7
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
47
0
0
0
0
0
47
0
0
0
0
0
0
34
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _