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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PAK7 All Species: 25.45
Human Site: Y160 Identified Species: 40
UniProt: Q9P286 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.21
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P286 NP_065074.1 719 80745 Y160 G D D L D P Y Y R G S H A A K
Chimpanzee Pan troglodytes XP_525261 777 87548 Y218 G D D L D P Y Y R G S H A A K
Rhesus Macaque Macaca mulatta XP_001113709 777 87522 Y218 G D D L D P Y Y R G S H A A K
Dog Lupus familis XP_542895 719 81009 Y160 G D D L D P F Y K G S H V A K
Cat Felis silvestris
Mouse Mus musculus Q8C015 719 80930 Y160 G D D L D L Y Y K S S H A A K
Rat Rattus norvegicus P35465 544 60559 D10 N N G L D V Q D K P P A P P M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514843 722 81837 Y160 G E E L D R C Y K S S H G T R
Chicken Gallus gallus XP_415031 787 88575 Y224 G E E L D R Y Y K G G Y A A K
Frog Xenopus laevis NP_001082100 650 73749 Q116 P R E D R F H Q E N G M S E V
Zebra Danio Brachydanio rerio NP_998127 711 78596 S160 L G P G P I R S P F Y P D A M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VXE5 639 69601 N105 M G S M A P M N P M A P G A H
Honey Bee Apis mellifera XP_001122147 624 70155 E90 K G R T F S G E K N T E N G L
Nematode Worm Caenorhab. elegans Q17850 572 63863 P38 L K P L P K E P E A T K K K K
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q03497 939 102344 S330 S N N S S S S S I T T A L R I
Red Bread Mold Neurospora crassa Q7RZD3 954 103773 D375 E S G I T E K D R R E H P Q I
Conservation
Percent
Protein Identity: 100 92.2 91.8 96.9 N.A. 93.8 31.2 N.A. 85.8 75.7 53.1 64.9 N.A. 45.6 45.4 31.1 N.A.
Protein Similarity: 100 92.4 92.2 98.3 N.A. 96.8 48.6 N.A. 92.5 82 64.8 75 N.A. 58.2 61 47 N.A.
P-Site Identity: 100 100 100 80 N.A. 80 13.3 N.A. 40 60 0 6.6 N.A. 13.3 0 13.3 N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 86.6 26.6 N.A. 66.6 86.6 20 6.6 N.A. 26.6 13.3 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 27 27.7
Protein Similarity: N.A. N.A. N.A. N.A. 44.2 42.6
P-Site Identity: N.A. N.A. N.A. N.A. 0 13.3
P-Site Similarity: N.A. N.A. N.A. N.A. 20 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 7 0 0 0 0 7 7 14 34 54 0 % A
% Cys: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % C
% Asp: 0 34 34 7 54 0 0 14 0 0 0 0 7 0 0 % D
% Glu: 7 14 20 0 0 7 7 7 14 0 7 7 0 7 0 % E
% Phe: 0 0 0 0 7 7 7 0 0 7 0 0 0 0 0 % F
% Gly: 47 20 14 7 0 0 7 0 0 34 14 0 14 7 0 % G
% His: 0 0 0 0 0 0 7 0 0 0 0 47 0 0 7 % H
% Ile: 0 0 0 7 0 7 0 0 7 0 0 0 0 0 14 % I
% Lys: 7 7 0 0 0 7 7 0 40 0 0 7 7 7 47 % K
% Leu: 14 0 0 60 0 7 0 0 0 0 0 0 7 0 7 % L
% Met: 7 0 0 7 0 0 7 0 0 7 0 7 0 0 14 % M
% Asn: 7 14 7 0 0 0 0 7 0 14 0 0 7 0 0 % N
% Pro: 7 0 14 0 14 34 0 7 14 7 7 14 14 7 0 % P
% Gln: 0 0 0 0 0 0 7 7 0 0 0 0 0 7 0 % Q
% Arg: 0 7 7 0 7 14 7 0 27 7 0 0 0 7 7 % R
% Ser: 7 7 7 7 7 14 7 14 0 14 40 0 7 0 0 % S
% Thr: 0 0 0 7 7 0 0 0 0 7 20 0 0 7 0 % T
% Val: 0 0 0 0 0 7 0 0 0 0 0 0 7 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 34 47 0 0 7 7 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _