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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PAK7
All Species:
19.09
Human Site:
Y199
Identified Species:
30
UniProt:
Q9P286
Number Species:
14
Phosphosite Substitution
Charge Score:
0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P286
NP_065074.1
719
80745
Y199
F
A
R
F
S
A
D
Y
H
S
H
L
D
S
L
Chimpanzee
Pan troglodytes
XP_525261
777
87548
Y257
F
A
R
F
S
A
D
Y
H
S
H
L
D
S
L
Rhesus Macaque
Macaca mulatta
XP_001113709
777
87522
Y257
F
A
R
F
S
A
D
Y
H
S
H
L
D
S
L
Dog
Lupus familis
XP_542895
719
81009
Y199
L
A
R
F
P
L
D
Y
H
T
H
L
D
S
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8C015
719
80930
Y199
L
A
G
F
P
V
D
Y
H
T
H
L
D
S
L
Rat
Rattus norvegicus
P35465
544
60559
E46
K
P
L
P
P
N
P
E
E
K
K
K
K
D
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514843
722
81837
A201
R
F
P
S
D
Y
H
A
H
M
E
A
L
N
K
Chicken
Gallus gallus
XP_415031
787
88575
V267
L
P
D
Y
H
A
Q
V
E
A
K
P
K
P
L
Frog
Xenopus laevis
NP_001082100
650
73749
E152
R
R
E
R
Q
R
E
E
H
R
A
V
P
Q
Q
Zebra Danio
Brachydanio rerio
NP_998127
711
78596
Y202
G
P
V
G
R
R
D
Y
R
A
S
L
G
G
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VXE5
639
69601
S141
K
T
S
H
V
A
R
S
N
S
L
R
S
S
S
Honey Bee
Apis mellifera
XP_001122147
624
70155
N126
R
D
Y
R
H
N
N
N
L
P
P
S
V
P
E
Nematode Worm
Caenorhab. elegans
Q17850
572
63863
E74
I
S
R
P
S
N
F
E
H
T
I
H
V
G
Y
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03497
939
102344
T370
E
E
W
E
K
L
L
T
S
S
G
I
S
K
R
Red Bread Mold
Neurospora crassa
Q7RZD3
954
103773
P424
P
P
V
T
G
T
A
P
L
V
L
Q
T
G
V
Conservation
Percent
Protein Identity:
100
92.2
91.8
96.9
N.A.
93.8
31.2
N.A.
85.8
75.7
53.1
64.9
N.A.
45.6
45.4
31.1
N.A.
Protein Similarity:
100
92.4
92.2
98.3
N.A.
96.8
48.6
N.A.
92.5
82
64.8
75
N.A.
58.2
61
47
N.A.
P-Site Identity:
100
100
100
73.3
N.A.
66.6
0
N.A.
6.6
13.3
6.6
20
N.A.
20
0
20
N.A.
P-Site Similarity:
100
100
100
80
N.A.
73.3
0
N.A.
13.3
26.6
20
26.6
N.A.
26.6
6.6
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27
27.7
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.2
42.6
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
34
0
0
0
34
7
7
0
14
7
7
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
7
0
7
0
40
0
0
0
0
0
34
7
0
% D
% Glu:
7
7
7
7
0
0
7
20
14
0
7
0
0
0
7
% E
% Phe:
20
7
0
34
0
0
7
0
0
0
0
0
0
0
0
% F
% Gly:
7
0
7
7
7
0
0
0
0
0
7
0
7
20
0
% G
% His:
0
0
0
7
14
0
7
0
54
0
34
7
0
0
0
% H
% Ile:
7
0
0
0
0
0
0
0
0
0
7
7
0
0
0
% I
% Lys:
14
0
0
0
7
0
0
0
0
7
14
7
14
7
7
% K
% Leu:
20
0
7
0
0
14
7
0
14
0
14
40
7
0
40
% L
% Met:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
20
7
7
7
0
0
0
0
7
0
% N
% Pro:
7
27
7
14
20
0
7
7
0
7
7
7
7
14
0
% P
% Gln:
0
0
0
0
7
0
7
0
0
0
0
7
0
7
7
% Q
% Arg:
20
7
34
14
7
14
7
0
7
7
0
7
0
0
14
% R
% Ser:
0
7
7
7
27
0
0
7
7
34
7
7
14
40
14
% S
% Thr:
0
7
0
7
0
7
0
7
0
20
0
0
7
0
0
% T
% Val:
0
0
14
0
7
7
0
7
0
7
0
7
14
0
7
% V
% Trp:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
7
0
7
0
40
0
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _