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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PAK7 All Species: 20.61
Human Site: Y219 Identified Species: 32.38
UniProt: Q9P286 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P286 NP_065074.1 719 80745 Y219 Y S D L K W E Y Q R A S S S S
Chimpanzee Pan troglodytes XP_525261 777 87548 Y277 Y S D L K W E Y Q R A S S S S
Rhesus Macaque Macaca mulatta XP_001113709 777 87522 Y277 Y S D L K W E Y Q R A S S S S
Dog Lupus familis XP_542895 719 81009 Y219 Y S D L K W E Y Q R A S S S S
Cat Felis silvestris
Mouse Mus musculus Q8C015 719 80930 Y219 Y G D L R W D Y Q R A S S S S
Rat Rattus norvegicus P35465 544 60559 K66 L A G D K T N K K K E K E R P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514843 722 81837 R221 G L P W D Y Q R V S S A S P L
Chicken Gallus gallus XP_415031 787 88575 P287 K L E Y Q R I P S G S S L D Y
Frog Xenopus laevis NP_001082100 650 73749 P172 P S N K H R P P P P D Y P K D
Zebra Danio Brachydanio rerio NP_998127 711 78596 S222 D A P L G T P S R L S L R S D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VXE5 639 69601 S161 R V A N V P P S V P E E E G P
Honey Bee Apis mellifera XP_001122147 624 70155 S146 S N T N Q I Q S Y T T N F G K
Nematode Worm Caenorhab. elegans Q17850 572 63863 A94 E F T G M P E A W A R L L T D
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q03497 939 102344 V390 M Q A V M D I V K F Y Q D V T
Red Bread Mold Neurospora crassa Q7RZD3 954 103773 P444 P M S P M I S P P A S P R F P
Conservation
Percent
Protein Identity: 100 92.2 91.8 96.9 N.A. 93.8 31.2 N.A. 85.8 75.7 53.1 64.9 N.A. 45.6 45.4 31.1 N.A.
Protein Similarity: 100 92.4 92.2 98.3 N.A. 96.8 48.6 N.A. 92.5 82 64.8 75 N.A. 58.2 61 47 N.A.
P-Site Identity: 100 100 100 100 N.A. 80 6.6 N.A. 6.6 6.6 6.6 13.3 N.A. 0 0 6.6 N.A.
P-Site Similarity: 100 100 100 100 N.A. 93.3 26.6 N.A. 33.3 26.6 13.3 33.3 N.A. 0 26.6 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 27 27.7
Protein Similarity: N.A. N.A. N.A. N.A. 44.2 42.6
P-Site Identity: N.A. N.A. N.A. N.A. 0 0
P-Site Similarity: N.A. N.A. N.A. N.A. 20 6.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 14 14 0 0 0 0 7 0 14 34 7 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 0 34 7 7 7 7 0 0 0 7 0 7 7 20 % D
% Glu: 7 0 7 0 0 0 34 0 0 0 14 7 14 0 0 % E
% Phe: 0 7 0 0 0 0 0 0 0 7 0 0 7 7 0 % F
% Gly: 7 7 7 7 7 0 0 0 0 7 0 0 0 14 0 % G
% His: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 14 14 0 0 0 0 0 0 0 0 % I
% Lys: 7 0 0 7 34 0 0 7 14 7 0 7 0 7 7 % K
% Leu: 7 14 0 40 0 0 0 0 0 7 0 14 14 0 7 % L
% Met: 7 7 0 0 20 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 7 7 14 0 0 7 0 0 0 0 7 0 0 0 % N
% Pro: 14 0 14 7 0 14 20 20 14 14 0 7 7 7 20 % P
% Gln: 0 7 0 0 14 0 14 0 34 0 0 7 0 0 0 % Q
% Arg: 7 0 0 0 7 14 0 7 7 34 7 0 14 7 0 % R
% Ser: 7 34 7 0 0 0 7 20 7 7 27 40 40 40 34 % S
% Thr: 0 0 14 0 0 14 0 0 0 7 7 0 0 7 7 % T
% Val: 0 7 0 7 7 0 0 7 14 0 0 0 0 7 0 % V
% Trp: 0 0 0 7 0 34 0 0 7 0 0 0 0 0 0 % W
% Tyr: 34 0 0 7 0 7 0 34 7 0 7 7 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _