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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PAK7 All Species: 26.97
Human Site: Y373 Identified Species: 42.38
UniProt: Q9P286 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P286 NP_065074.1 719 80745 Y373 Y S S S S H Q Y P S G Y H K A
Chimpanzee Pan troglodytes XP_525261 777 87548 Y431 Y S S S S H Q Y P S G Y H K A
Rhesus Macaque Macaca mulatta XP_001113709 777 87522 Y431 Y S S S S H Q Y P S G Y H K A
Dog Lupus familis XP_542895 719 81009 Y373 Y S S S S H Q Y P S G Y H K A
Cat Felis silvestris
Mouse Mus musculus Q8C015 719 80930 Y373 Y S S G S H Q Y P S G Y H K A
Rat Rattus norvegicus P35465 544 60559 P220 T R D V A T S P I S P T E N N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514843 722 81837 Y375 Y S T S G Y Q Y P S G Y H K A
Chicken Gallus gallus XP_415031 787 88575 Y441 Y S S S S Y Q Y P L V Y H K A
Frog Xenopus laevis NP_001082100 650 73749 Q326 P E K P H P T Q L A P H S S D
Zebra Danio Brachydanio rerio NP_998127 711 78596 P376 H P P S Q P S P P Y T P A G A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VXE5 639 69601 A315 L A K S A S R A S S S S G G A
Honey Bee Apis mellifera XP_001122147 624 70155 N300 Q L S T H N V N K Y S Q S A L
Nematode Worm Caenorhab. elegans Q17850 572 63863 E248 I Y T K P K E E E E K I P D L
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q03497 939 102344 S544 P P I P P T K S K T S P I I S
Red Bread Mold Neurospora crassa Q7RZD3 954 103773 G598 Q A Q A A M S G Q L S R A A S
Conservation
Percent
Protein Identity: 100 92.2 91.8 96.9 N.A. 93.8 31.2 N.A. 85.8 75.7 53.1 64.9 N.A. 45.6 45.4 31.1 N.A.
Protein Similarity: 100 92.4 92.2 98.3 N.A. 96.8 48.6 N.A. 92.5 82 64.8 75 N.A. 58.2 61 47 N.A.
P-Site Identity: 100 100 100 100 N.A. 93.3 6.6 N.A. 80 80 0 20 N.A. 20 6.6 0 N.A.
P-Site Similarity: 100 100 100 100 N.A. 93.3 13.3 N.A. 93.3 86.6 13.3 26.6 N.A. 40 20 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 27 27.7
Protein Similarity: N.A. N.A. N.A. N.A. 44.2 42.6
P-Site Identity: N.A. N.A. N.A. N.A. 0 0
P-Site Similarity: N.A. N.A. N.A. N.A. 20 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 14 0 7 20 0 0 7 0 7 0 0 14 14 60 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 7 0 0 0 0 0 0 0 0 0 0 7 7 % D
% Glu: 0 7 0 0 0 0 7 7 7 7 0 0 7 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 7 7 0 0 7 0 0 40 0 7 14 0 % G
% His: 7 0 0 0 14 34 0 0 0 0 0 7 47 0 0 % H
% Ile: 7 0 7 0 0 0 0 0 7 0 0 7 7 7 0 % I
% Lys: 0 0 14 7 0 7 7 0 14 0 7 0 0 47 0 % K
% Leu: 7 7 0 0 0 0 0 0 7 14 0 0 0 0 14 % L
% Met: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 7 0 7 0 0 0 0 0 7 7 % N
% Pro: 14 14 7 14 14 14 0 14 54 0 14 14 7 0 0 % P
% Gln: 14 0 7 0 7 0 47 7 7 0 0 7 0 0 0 % Q
% Arg: 0 7 0 0 0 0 7 0 0 0 0 7 0 0 0 % R
% Ser: 0 47 47 54 40 7 20 7 7 54 27 7 14 7 14 % S
% Thr: 7 0 14 7 0 14 7 0 0 7 7 7 0 0 0 % T
% Val: 0 0 0 7 0 0 7 0 0 0 7 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 47 7 0 0 0 14 0 47 0 14 0 47 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _