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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PAK7
All Species:
40
Human Site:
Y643
Identified Species:
62.86
UniProt:
Q9P286
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P286
NP_065074.1
719
80745
Y643
M
I
D
G
E
P
P
Y
F
N
E
P
P
L
Q
Chimpanzee
Pan troglodytes
XP_525261
777
87548
Y701
M
I
D
G
E
P
P
Y
F
N
E
P
P
L
Q
Rhesus Macaque
Macaca mulatta
XP_001113709
777
87522
Y701
M
I
D
G
E
P
P
Y
F
N
E
P
P
L
Q
Dog
Lupus familis
XP_542895
719
81009
Y643
M
I
D
G
E
P
P
Y
F
N
E
P
P
L
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8C015
719
80930
Y643
M
I
D
G
E
P
P
Y
F
N
E
P
P
L
Q
Rat
Rattus norvegicus
P35465
544
60559
A471
L
N
E
N
P
L
R
A
L
Y
L
I
A
T
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514843
722
81837
Y646
M
I
D
G
E
P
P
Y
F
N
E
P
P
L
Q
Chicken
Gallus gallus
XP_415031
787
88575
Y711
M
I
D
G
E
P
P
Y
F
N
E
P
P
L
Q
Frog
Xenopus laevis
NP_001082100
650
73749
E577
G
E
P
P
Y
F
N
E
P
P
L
K
A
M
K
Zebra Danio
Brachydanio rerio
NP_998127
711
78596
Y635
M
V
D
G
E
P
P
Y
F
N
E
P
P
L
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VXE5
639
69601
P566
E
P
P
F
F
N
E
P
P
L
Q
A
M
R
R
Honey Bee
Apis mellifera
XP_001122147
624
70155
P551
P
P
F
F
N
E
P
P
L
Q
A
M
R
R
I
Nematode Worm
Caenorhab. elegans
Q17850
572
63863
Y499
E
N
P
L
R
A
I
Y
L
I
A
T
N
G
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03497
939
102344
Y814
M
I
E
G
E
P
P
Y
L
N
E
T
P
L
R
Red Bread Mold
Neurospora crassa
Q7RZD3
954
103773
Y868
M
I
E
G
E
P
P
Y
L
T
E
S
P
L
R
Conservation
Percent
Protein Identity:
100
92.2
91.8
96.9
N.A.
93.8
31.2
N.A.
85.8
75.7
53.1
64.9
N.A.
45.6
45.4
31.1
N.A.
Protein Similarity:
100
92.4
92.2
98.3
N.A.
96.8
48.6
N.A.
92.5
82
64.8
75
N.A.
58.2
61
47
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
0
N.A.
100
100
0
93.3
N.A.
0
6.6
6.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
13.3
N.A.
100
100
13.3
100
N.A.
13.3
6.6
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27
27.7
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.2
42.6
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
73.3
66.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
86.6
80
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
7
0
7
0
0
14
7
14
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
54
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
14
7
20
0
67
7
7
7
0
0
67
0
0
0
0
% E
% Phe:
0
0
7
14
7
7
0
0
54
0
0
0
0
0
0
% F
% Gly:
7
0
0
67
0
0
0
0
0
0
0
0
0
7
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
60
0
0
0
0
7
0
0
7
0
7
0
0
7
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
14
% K
% Leu:
7
0
0
7
0
7
0
0
34
7
14
0
0
67
0
% L
% Met:
67
0
0
0
0
0
0
0
0
0
0
7
7
7
0
% M
% Asn:
0
14
0
7
7
7
7
0
0
60
0
0
7
0
7
% N
% Pro:
7
14
20
7
7
67
74
14
14
7
0
54
67
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
7
7
0
0
0
54
% Q
% Arg:
0
0
0
0
7
0
7
0
0
0
0
0
7
14
20
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
7
0
14
0
7
0
% T
% Val:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
7
0
0
74
0
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _