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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MST4 All Species: 10.61
Human Site: S282 Identified Species: 19.44
UniProt: Q9P289 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P289 NP_057626.2 416 46529 S282 V K N S K K T S Y L T E L I D
Chimpanzee Pan troglodytes XP_521266 579 63278 P421 I E L A K G E P P N S D M H P
Rhesus Macaque Macaca mulatta A4K2T0 487 55587 I289 K S A K G V S I L R D L I N E
Dog Lupus familis XP_549261 626 68824 S492 V K N S K K T S Y L T E L I D
Cat Felis silvestris
Mouse Mus musculus Q99JT2 416 46595 S282 V K N S K K T S Y L T E L I D
Rat Rattus norvegicus O54748 491 56103 K298 I T E G M E I K A K R H E E Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514828 344 38700 D217 S Y L T E L I D R F K R W K A
Chicken Gallus gallus Q5ZJK4 486 55318 I288 K S A K G A S I L R D L I N E
Frog Xenopus laevis Q6IP06 493 56486 K297 I T E A M D I K A K R H E E L
Zebra Danio Brachydanio rerio Q7ZUQ3 492 56062 I285 V G A K P V S I L R D L I T E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8T0S6 669 75091 I301 R N A K H R S I L K P M L E E
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9NB31 497 55620 C292 F I K N A P G C D I M Q L M I
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P38692 1080 117043 T284 R A H K A T P T S I L K E L I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 60.4 39.2 66.2 N.A. 98 38.7 N.A. 73 38.4 38.1 37.4 N.A. 28.7 N.A. 34.8 N.A.
Protein Similarity: 100 62 56.8 66.4 N.A. 99.2 57 N.A. 78.8 56.3 55.9 55.6 N.A. 43.9 N.A. 53.7 N.A.
P-Site Identity: 100 6.6 0 100 N.A. 100 0 N.A. 0 0 0 6.6 N.A. 6.6 N.A. 6.6 N.A.
P-Site Similarity: 100 46.6 20 100 N.A. 100 13.3 N.A. 13.3 20 13.3 26.6 N.A. 26.6 N.A. 33.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.5 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 28.7 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 31 16 16 8 0 0 16 0 0 0 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 8 0 8 8 0 24 8 0 0 24 % D
% Glu: 0 8 16 0 8 8 8 0 0 0 0 24 24 24 31 % E
% Phe: 8 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % F
% Gly: 0 8 0 8 16 8 8 0 0 0 0 0 0 0 0 % G
% His: 0 0 8 0 8 0 0 0 0 0 0 16 0 8 0 % H
% Ile: 24 8 0 0 0 0 24 31 0 16 0 0 24 24 16 % I
% Lys: 16 24 8 39 31 24 0 16 0 24 8 8 0 8 0 % K
% Leu: 0 0 16 0 0 8 0 0 31 24 8 24 39 8 8 % L
% Met: 0 0 0 0 16 0 0 0 0 0 8 8 8 8 0 % M
% Asn: 0 8 24 8 0 0 0 0 0 8 0 0 0 16 0 % N
% Pro: 0 0 0 0 8 8 8 8 8 0 8 0 0 0 8 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 8 % Q
% Arg: 16 0 0 0 0 8 0 0 8 24 16 8 0 0 0 % R
% Ser: 8 16 0 24 0 0 31 24 8 0 8 0 0 0 0 % S
% Thr: 0 16 0 8 0 8 24 8 0 0 24 0 0 8 0 % T
% Val: 31 0 0 0 0 16 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % W
% Tyr: 0 8 0 0 0 0 0 0 24 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _