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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: COPZ2 All Species: 40
Human Site: S170 Identified Species: 73.33
UniProt: Q9P299 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P299 NP_057513.1 210 23548 S170 D G G V I L E S D P Q Q V I Q
Chimpanzee Pan troglodytes XP_001156445 198 22357 S158 D G G V I L E S D P Q Q V V H
Rhesus Macaque Macaca mulatta XP_001109692 197 22177 S157 D G G V I L E S D P Q Q V V H
Dog Lupus familis XP_548170 247 27314 S207 D G G V I L E S D A Q Q V I Q
Cat Felis silvestris
Mouse Mus musculus Q9JHH9 205 22916 S165 D G G V I L E S D P Q Q V I Q
Rat Rattus norvegicus NP_001101764 207 23249 S167 D G G V I L E S D P Q Q V I Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001085450 177 20156 S137 D G G V I L E S D P Q Q V V H
Zebra Danio Brachydanio rerio NP_571582 189 21495 S138 D G G V I L E S D P Q Q V M E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_623380 201 22791 A161 D G G I I L D A D A T S V V Q
Nematode Worm Caenorhab. elegans O17901 184 20738 T140 D E G I I M E T D A Q A V V Q
Sea Urchin Strong. purpuratus XP_785136 177 19813 A137 D E G I I L E A D P I A V A Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q84LG4 179 19720 T137 D Q G V V L E T D P N V I A G
Baker's Yeast Sacchar. cerevisiae P53600 189 21669 T143 D N G V I L E T D S N T I A S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 60.9 65.7 72.4 N.A. 89.5 90.4 N.A. N.A. N.A. 61.9 66.1 N.A. N.A. 52.3 42.3 51.4
Protein Similarity: 100 73.3 77.1 75.7 N.A. 92.8 93.3 N.A. N.A. N.A. 73.8 76.1 N.A. N.A. 71.4 66.1 68.1
P-Site Identity: 100 86.6 86.6 93.3 N.A. 100 100 N.A. N.A. N.A. 86.6 86.6 N.A. N.A. 53.3 53.3 60
P-Site Similarity: 100 93.3 93.3 93.3 N.A. 100 100 N.A. N.A. N.A. 93.3 100 N.A. N.A. 80 80 73.3
Percent
Protein Identity: N.A. N.A. N.A. 38.1 25.2 N.A.
Protein Similarity: N.A. N.A. N.A. 54.2 46.1 N.A.
P-Site Identity: N.A. N.A. N.A. 46.6 46.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 66.6 60 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 16 0 24 0 16 0 24 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 100 0 0 0 0 0 8 0 100 0 0 0 0 0 0 % D
% Glu: 0 16 0 0 0 0 93 0 0 0 0 0 0 0 8 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 70 100 0 0 0 0 0 0 0 0 0 0 0 8 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 24 % H
% Ile: 0 0 0 24 93 0 0 0 0 0 8 0 16 31 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 93 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 8 0 0 0 0 0 0 0 8 0 % M
% Asn: 0 8 0 0 0 0 0 0 0 0 16 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 70 0 0 0 0 0 % P
% Gln: 0 8 0 0 0 0 0 0 0 0 70 62 0 0 54 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 62 0 8 0 8 0 0 8 % S
% Thr: 0 0 0 0 0 0 0 24 0 0 8 8 0 0 0 % T
% Val: 0 0 0 77 8 0 0 0 0 0 0 8 85 39 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _