Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: COPZ2 All Species: 32.42
Human Site: T189 Identified Species: 59.44
UniProt: Q9P299 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P299 NP_057513.1 210 23548 T189 R A D D G G L T E Q S V A Q V
Chimpanzee Pan troglodytes XP_001156445 198 22357 T177 R G E D V P L T E Q T V S Q V
Rhesus Macaque Macaca mulatta XP_001109692 197 22177 T176 R G E D V P L T E Q T V S Q V
Dog Lupus familis XP_548170 247 27314 T226 R A D D S S L T E Q S V A Q V
Cat Felis silvestris
Mouse Mus musculus Q9JHH9 205 22916 T184 R T D D S G L T E Q S V A Q V
Rat Rattus norvegicus NP_001101764 207 23249 T186 R T D D S G L T E Q S V A Q V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001085450 177 20156 T156 R G D D V P L T E Q T V S Q V
Zebra Danio Brachydanio rerio NP_571582 189 21495 K168 V A Q H I T E K L A L T T N V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_623380 201 22791 G180 R T D D I P L G E Q T V A Q V
Nematode Worm Caenorhab. elegans O17901 184 20738 S159 K S D E V S F S D Q S V S Q I
Sea Urchin Strong. purpuratus XP_785136 177 19813 S156 R G D D V P I S E Q T M S Q V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q84LG4 179 19720 S158 T E A S G S L S E Q T L T Q A
Baker's Yeast Sacchar. cerevisiae P53600 189 21669 L166 E P Q M A L D L D K G F L G A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 60.9 65.7 72.4 N.A. 89.5 90.4 N.A. N.A. N.A. 61.9 66.1 N.A. N.A. 52.3 42.3 51.4
Protein Similarity: 100 73.3 77.1 75.7 N.A. 92.8 93.3 N.A. N.A. N.A. 73.8 76.1 N.A. N.A. 71.4 66.1 68.1
P-Site Identity: 100 60 60 86.6 N.A. 86.6 86.6 N.A. N.A. N.A. 66.6 13.3 N.A. N.A. 66.6 33.3 46.6
P-Site Similarity: 100 80 80 86.6 N.A. 86.6 86.6 N.A. N.A. N.A. 80 13.3 N.A. N.A. 73.3 80 80
Percent
Protein Identity: N.A. N.A. N.A. 38.1 25.2 N.A.
Protein Similarity: N.A. N.A. N.A. 54.2 46.1 N.A.
P-Site Identity: N.A. N.A. N.A. 33.3 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 53.3 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 24 8 0 8 0 0 0 0 8 0 0 39 0 16 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 62 70 0 0 8 0 16 0 0 0 0 0 0 % D
% Glu: 8 8 16 8 0 0 8 0 77 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 8 0 0 0 0 8 0 0 0 % F
% Gly: 0 31 0 0 16 24 0 8 0 0 8 0 0 8 0 % G
% His: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 16 0 8 0 0 0 0 0 0 0 8 % I
% Lys: 8 0 0 0 0 0 0 8 0 8 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 8 70 8 8 0 8 8 8 0 0 % L
% Met: 0 0 0 8 0 0 0 0 0 0 0 8 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % N
% Pro: 0 8 0 0 0 39 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 16 0 0 0 0 0 0 85 0 0 0 85 0 % Q
% Arg: 70 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 8 0 8 24 24 0 24 0 0 39 0 39 0 0 % S
% Thr: 8 24 0 0 0 8 0 54 0 0 47 8 16 0 0 % T
% Val: 8 0 0 0 39 0 0 0 0 0 0 70 0 0 77 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _