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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIAA1430 All Species: 8.79
Human Site: Y422 Identified Species: 24.17
UniProt: Q9P2B7 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P2B7 NP_065878.1 532 59475 Y422 A D H P P K L Y H S A L N R Q
Chimpanzee Pan troglodytes XP_001163296 528 58990 Y418 A D H P P K L Y H S A L N R Q
Rhesus Macaque Macaca mulatta XP_001084789 529 59268 Y419 T D H P P K L Y H S A L N R Q
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q6ZPR1 541 60818 L430 S I G H P P K L Y H S A L N R
Rat Rattus norvegicus Q66H34 548 61724 L431 S L G H P P K L Y H S A L N R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507043 345 36646 G249 S D E S E A T G T A G T P R S
Chicken Gallus gallus XP_001232315 269 29262 H173 S S F S S D A H S D S S L S D
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_997943 449 50583 R353 R S S A P T V R L Y H S A L N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796877 508 56869 I394 R E Q R R I E I E N M Q I L K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.4 95.4 N.A. N.A. 70.4 69.7 N.A. 24.6 20.2 N.A. 27.8 N.A. N.A. N.A. N.A. 26.3
Protein Similarity: 100 97.1 97.3 N.A. N.A. 80 79.7 N.A. 36.6 31.3 N.A. 44.5 N.A. N.A. N.A. N.A. 44.7
P-Site Identity: 100 100 93.3 N.A. N.A. 6.6 6.6 N.A. 13.3 0 N.A. 6.6 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 93.3 N.A. N.A. 33.3 33.3 N.A. 26.6 20 N.A. 13.3 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 23 0 0 12 0 12 12 0 0 12 34 23 12 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 45 0 0 0 12 0 0 0 12 0 0 0 0 12 % D
% Glu: 0 12 12 0 12 0 12 0 12 0 0 0 0 0 0 % E
% Phe: 0 0 12 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 23 0 0 0 0 12 0 0 12 0 0 0 0 % G
% His: 0 0 34 23 0 0 0 12 34 23 12 0 0 0 0 % H
% Ile: 0 12 0 0 0 12 0 12 0 0 0 0 12 0 0 % I
% Lys: 0 0 0 0 0 34 23 0 0 0 0 0 0 0 12 % K
% Leu: 0 12 0 0 0 0 34 23 12 0 0 34 34 23 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 12 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 12 0 0 34 23 12 % N
% Pro: 0 0 0 34 67 23 0 0 0 0 0 0 12 0 0 % P
% Gln: 0 0 12 0 0 0 0 0 0 0 0 12 0 0 34 % Q
% Arg: 23 0 0 12 12 0 0 12 0 0 0 0 0 45 23 % R
% Ser: 45 23 12 23 12 0 0 0 12 34 34 23 0 12 12 % S
% Thr: 12 0 0 0 0 12 12 0 12 0 0 12 0 0 0 % T
% Val: 0 0 0 0 0 0 12 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 34 23 12 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _