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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM181
All Species:
4.24
Human Site:
S580
Identified Species:
15.56
UniProt:
Q9P2C4
Number Species:
6
Phosphosite Substitution
Charge Score:
0.67
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P2C4
NP_065874.1
612
69325
S580
A
F
S
M
L
N
D
S
D
D
D
V
I
Y
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_855028
441
51317
D410
F
S
M
L
N
D
S
D
D
D
V
I
Y
G
S
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001128255
476
55261
D445
F
S
M
L
N
D
S
D
D
D
V
I
Y
G
S
Zebra Danio
Brachydanio rerio
NP_001038305
524
61042
E493
M
L
N
D
S
D
D
E
V
I
Y
G
S
D
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651004
547
63142
S516
A
I
S
M
I
D
D
S
D
E
D
V
V
Y
G
Honey Bee
Apis mellifera
XP_624574
525
61101
M494
K
D
N
P
T
F
S
M
I
N
D
S
D
E
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001179944
536
61532
E505
P
T
F
S
M
L
N
E
S
E
D
E
L
I
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
68.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
62.7
60.9
N.A.
40.3
40.5
N.A.
39
Protein Similarity:
100
N.A.
N.A.
71.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
70.2
70.7
N.A.
55.5
57.6
N.A.
58.6
P-Site Identity:
100
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
6.6
N.A.
66.6
6.6
N.A.
6.6
P-Site Similarity:
100
N.A.
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
20
N.A.
93.3
20
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
29
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
15
0
15
0
58
43
29
58
43
58
0
15
15
0
% D
% Glu:
0
0
0
0
0
0
0
29
0
29
0
15
0
15
15
% E
% Phe:
29
15
15
0
0
15
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
15
0
29
29
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
15
0
0
15
0
0
0
15
15
0
29
15
15
0
% I
% Lys:
15
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
15
0
29
15
15
0
0
0
0
0
0
15
0
0
% L
% Met:
15
0
29
29
15
0
0
15
0
0
0
0
0
0
0
% M
% Asn:
0
0
29
0
29
15
15
0
0
15
0
0
0
0
0
% N
% Pro:
15
0
0
15
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
29
29
15
15
0
43
29
15
0
0
15
15
0
29
% S
% Thr:
0
15
0
0
15
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
15
0
29
29
15
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
15
0
29
29
29
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _