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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM181
All Species:
0
Human Site:
T412
Identified Species:
0
UniProt:
Q9P2C4
Number Species:
6
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P2C4
NP_065874.1
612
69325
T412
Q
G
E
R
K
C
L
T
F
Y
L
P
K
F
F
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_855028
441
51317
D246
L
R
K
F
S
M
R
D
W
G
M
E
Q
K
W
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001128255
476
55261
K281
C
L
T
F
Y
L
P
K
L
L
I
V
G
L
L
Zebra Danio
Brachydanio rerio
NP_001038305
524
61042
L329
L
T
F
Y
L
P
K
L
L
M
V
G
L
L
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651004
547
63142
V352
V
R
F
Y
L
V
K
V
I
V
V
L
P
I
W
Honey Bee
Apis mellifera
XP_624574
525
61101
F330
N
E
R
R
L
I
T
F
Y
L
P
K
V
L
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001179944
536
61532
I341
W
L
C
A
Y
H
G
I
R
Q
S
D
R
K
W
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
68.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
62.7
60.9
N.A.
40.3
40.5
N.A.
39
Protein Similarity:
100
N.A.
N.A.
71.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
70.2
70.7
N.A.
55.5
57.6
N.A.
58.6
P-Site Identity:
100
N.A.
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
0
0
N.A.
0
6.6
N.A.
0
P-Site Similarity:
100
N.A.
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
13.3
N.A.
13.3
13.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
15
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
15
0
15
0
0
15
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
15
0
0
0
15
0
0
0
% D
% Glu:
0
15
15
0
0
0
0
0
0
0
0
15
0
0
0
% E
% Phe:
0
0
29
29
0
0
0
15
15
0
0
0
0
15
15
% F
% Gly:
0
15
0
0
0
0
15
0
0
15
0
15
15
0
0
% G
% His:
0
0
0
0
0
15
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
15
0
15
15
0
15
0
0
15
0
% I
% Lys:
0
0
15
0
15
0
29
15
0
0
0
15
15
29
0
% K
% Leu:
29
29
0
0
43
15
15
15
29
29
15
15
15
43
15
% L
% Met:
0
0
0
0
0
15
0
0
0
15
15
0
0
0
0
% M
% Asn:
15
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
15
15
0
0
0
15
15
15
0
0
% P
% Gln:
15
0
0
0
0
0
0
0
0
15
0
0
15
0
0
% Q
% Arg:
0
29
15
29
0
0
15
0
15
0
0
0
15
0
0
% R
% Ser:
0
0
0
0
15
0
0
0
0
0
15
0
0
0
0
% S
% Thr:
0
15
15
0
0
0
15
15
0
0
0
0
0
0
0
% T
% Val:
15
0
0
0
0
15
0
15
0
15
29
15
15
0
15
% V
% Trp:
15
0
0
0
0
0
0
0
15
0
0
0
0
0
58
% W
% Tyr:
0
0
0
29
29
0
0
0
15
15
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _