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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM181
All Species:
0
Human Site:
Y488
Identified Species:
0
UniProt:
Q9P2C4
Number Species:
6
Phosphosite Substitution
Charge Score:
-0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P2C4
NP_065874.1
612
69325
Y488
S
E
L
R
H
M
P
Y
V
D
L
R
L
K
F
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_855028
441
51317
L320
R
H
M
P
Y
V
D
L
R
L
K
F
L
T
A
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001128255
476
55261
L355
R
N
M
P
Y
V
D
L
R
L
K
F
L
T
A
Zebra Danio
Brachydanio rerio
NP_001038305
524
61042
R403
N
M
P
Y
S
D
L
R
L
K
F
L
T
A
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651004
547
63142
R426
S
M
P
Y
F
D
M
R
L
K
F
L
T
L
L
Honey Bee
Apis mellifera
XP_624574
525
61101
P404
Y
S
E
L
R
S
M
P
Y
F
D
L
R
L
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001179944
536
61532
I415
L
Y
L
L
F
L
V
I
R
A
F
T
E
L
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
68.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
62.7
60.9
N.A.
40.3
40.5
N.A.
39
Protein Similarity:
100
N.A.
N.A.
71.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
70.2
70.7
N.A.
55.5
57.6
N.A.
58.6
P-Site Identity:
100
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
0
N.A.
6.6
0
N.A.
6.6
P-Site Similarity:
100
N.A.
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
13.3
N.A.
13.3
0
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
15
0
0
0
15
29
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
29
29
0
0
15
15
0
0
0
0
% D
% Glu:
0
15
15
0
0
0
0
0
0
0
0
0
15
0
0
% E
% Phe:
0
0
0
0
29
0
0
0
0
15
43
29
0
0
15
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
15
0
0
15
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
15
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
29
29
0
0
15
0
% K
% Leu:
15
0
29
29
0
15
15
29
29
29
15
43
43
43
29
% L
% Met:
0
29
29
0
0
15
29
0
0
0
0
0
0
0
0
% M
% Asn:
15
15
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
29
29
0
0
15
15
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
29
0
0
15
15
0
0
29
43
0
0
15
15
0
29
% R
% Ser:
29
15
0
0
15
15
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
15
29
29
0
% T
% Val:
0
0
0
0
0
29
15
0
15
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
15
15
0
29
29
0
0
15
15
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _