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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HEATR5B
All Species:
8.79
Human Site:
S1579
Identified Species:
24.17
UniProt:
Q9P2D3
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P2D3
NP_061897.1
2071
224302
S1579
G
A
V
G
S
A
K
S
L
P
E
I
N
K
D
Chimpanzee
Pan troglodytes
XP_515406
2071
224316
S1579
G
A
M
G
S
A
K
S
L
P
E
I
N
K
D
Rhesus Macaque
Macaca mulatta
XP_001108090
2090
225671
I1568
C
Q
V
C
S
A
W
I
A
S
G
V
V
S
D
Dog
Lupus familis
XP_540148
2070
224505
S1579
G
A
T
P
S
T
K
S
L
P
E
I
N
K
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8C547
2070
224301
P1579
G
A
M
A
S
A
K
P
L
P
E
V
N
K
D
Rat
Rattus norvegicus
XP_002726722
2031
219785
P1540
G
A
M
A
S
A
K
P
L
P
E
V
N
K
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_419518
2073
224512
T1579
T
P
G
T
P
P
T
T
K
S
L
P
E
L
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q8JFV4
1998
216687
N1511
V
K
S
P
E
D
I
N
S
D
R
L
H
L
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780534
2231
242741
D1733
K
P
E
E
I
K
S
D
Y
F
H
L
M
I
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
53.6
97.5
N.A.
95.8
94
N.A.
N.A.
93
N.A.
53.1
N.A.
N.A.
N.A.
N.A.
53.9
Protein Similarity:
100
100
69.8
98.6
N.A.
97.5
95.9
N.A.
N.A.
96.3
N.A.
71.3
N.A.
N.A.
N.A.
N.A.
70.1
P-Site Identity:
100
93.3
26.6
80
N.A.
73.3
73.3
N.A.
N.A.
0
N.A.
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
33.3
80
N.A.
86.6
86.6
N.A.
N.A.
13.3
N.A.
20
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
56
0
23
0
56
0
0
12
0
0
0
0
0
0
% A
% Cys:
12
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
12
0
12
0
12
0
0
0
0
67
% D
% Glu:
0
0
12
12
12
0
0
0
0
0
56
0
12
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% F
% Gly:
56
0
12
23
0
0
0
0
0
0
12
0
0
0
12
% G
% His:
0
0
0
0
0
0
0
0
0
0
12
0
12
0
0
% H
% Ile:
0
0
0
0
12
0
12
12
0
0
0
34
0
12
12
% I
% Lys:
12
12
0
0
0
12
56
0
12
0
0
0
0
56
0
% K
% Leu:
0
0
0
0
0
0
0
0
56
0
12
23
0
23
0
% L
% Met:
0
0
34
0
0
0
0
0
0
0
0
0
12
0
0
% M
% Asn:
0
0
0
0
0
0
0
12
0
0
0
0
56
0
12
% N
% Pro:
0
23
0
23
12
12
0
23
0
56
0
12
0
0
0
% P
% Gln:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% R
% Ser:
0
0
12
0
67
0
12
34
12
23
0
0
0
12
0
% S
% Thr:
12
0
12
12
0
12
12
12
0
0
0
0
0
0
0
% T
% Val:
12
0
23
0
0
0
0
0
0
0
0
34
12
0
0
% V
% Trp:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _