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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HEATR5B
All Species:
18.18
Human Site:
S852
Identified Species:
50
UniProt:
Q9P2D3
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P2D3
NP_061897.1
2071
224302
S852
G
P
E
E
V
R
K
S
A
L
T
L
V
M
G
Chimpanzee
Pan troglodytes
XP_515406
2071
224316
S852
G
P
E
E
V
R
K
S
A
L
T
L
V
M
G
Rhesus Macaque
Macaca mulatta
XP_001108090
2090
225671
R856
L
T
E
E
V
I
Q
R
L
L
P
P
L
P
C
Dog
Lupus familis
XP_540148
2070
224505
S852
G
P
E
E
V
R
K
S
A
L
T
L
V
M
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8C547
2070
224301
S852
G
P
E
E
V
R
K
S
A
L
T
L
V
M
G
Rat
Rattus norvegicus
XP_002726722
2031
219785
P825
V
M
G
A
L
D
N
P
N
P
I
L
R
C
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_419518
2073
224512
S852
G
P
E
E
V
R
K
S
A
L
T
L
V
M
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q8JFV4
1998
216687
R832
E
G
S
N
P
L
L
R
C
M
A
A
E
G
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780534
2231
242741
A1007
V
N
T
K
V
R
N
A
A
Y
A
L
I
M
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
53.6
97.5
N.A.
95.8
94
N.A.
N.A.
93
N.A.
53.1
N.A.
N.A.
N.A.
N.A.
53.9
Protein Similarity:
100
100
69.8
98.6
N.A.
97.5
95.9
N.A.
N.A.
96.3
N.A.
71.3
N.A.
N.A.
N.A.
N.A.
70.1
P-Site Identity:
100
100
26.6
100
N.A.
100
6.6
N.A.
N.A.
100
N.A.
0
N.A.
N.A.
N.A.
N.A.
40
P-Site Similarity:
100
100
40
100
N.A.
100
13.3
N.A.
N.A.
100
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
12
0
0
0
12
67
0
23
12
0
0
12
% A
% Cys:
0
0
0
0
0
0
0
0
12
0
0
0
0
12
12
% C
% Asp:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% D
% Glu:
12
0
67
67
0
0
0
0
0
0
0
0
12
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
56
12
12
0
0
0
0
0
0
0
0
0
0
12
67
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
12
0
0
0
0
12
0
12
0
0
% I
% Lys:
0
0
0
12
0
0
56
0
0
0
0
0
0
0
0
% K
% Leu:
12
0
0
0
12
12
12
0
12
67
0
78
12
0
12
% L
% Met:
0
12
0
0
0
0
0
0
0
12
0
0
0
67
0
% M
% Asn:
0
12
0
12
0
0
23
0
12
0
0
0
0
0
0
% N
% Pro:
0
56
0
0
12
0
0
12
0
12
12
12
0
12
0
% P
% Gln:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
67
0
23
0
0
0
0
12
0
0
% R
% Ser:
0
0
12
0
0
0
0
56
0
0
0
0
0
0
0
% S
% Thr:
0
12
12
0
0
0
0
0
0
0
56
0
0
0
0
% T
% Val:
23
0
0
0
78
0
0
0
0
0
0
0
56
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _