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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM135A
All Species:
23.03
Human Site:
S404
Identified Species:
56.3
UniProt:
Q9P2D6
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P2D6
NP_001099001.1
1515
169840
S404
E
L
D
G
D
L
N
S
L
P
I
I
F
E
D
Chimpanzee
Pan troglodytes
XP_001138203
1515
169815
S404
E
L
D
G
D
L
N
S
L
P
I
I
F
E
D
Rhesus Macaque
Macaca mulatta
XP_001089896
1308
144316
D224
A
L
W
T
Q
F
L
D
T
V
T
L
H
S
Q
Dog
Lupus familis
XP_853259
1517
169912
S404
E
L
D
G
D
L
N
S
L
P
I
I
F
E
D
Cat
Felis silvestris
Mouse
Mus musculus
Q6NS59
1506
166838
S404
E
L
D
G
D
L
N
S
L
P
I
I
F
E
D
Rat
Rattus norvegicus
NP_001128069
1507
167117
S397
P
L
H
G
D
L
N
S
L
P
I
I
F
E
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510578
1506
167802
S394
E
L
D
G
D
L
N
S
L
P
I
I
F
E
D
Chicken
Gallus gallus
XP_419888
1500
166663
C395
L
P
P
L
P
I
E
C
S
E
L
D
G
D
T
Frog
Xenopus laevis
Q641I1
1376
154423
L292
L
C
N
Q
L
Q
L
L
S
D
P
E
E
I
T
Zebra Danio
Brachydanio rerio
NP_001139066
1338
148314
S254
N
L
L
R
A
Y
Q
S
L
F
C
Y
L
T
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
35.8
91
N.A.
83.8
81.6
N.A.
76
71.8
39.4
52.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
53.2
95.3
N.A.
91.2
89.4
N.A.
85.1
82.5
56.9
67.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
6.6
100
N.A.
100
86.6
N.A.
100
0
0
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
13.3
100
N.A.
100
86.6
N.A.
100
20
6.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
10
0
0
0
0
0
10
0
0
10
0
0
0
0
% C
% Asp:
0
0
50
0
60
0
0
10
0
10
0
10
0
10
60
% D
% Glu:
50
0
0
0
0
0
10
0
0
10
0
10
10
60
0
% E
% Phe:
0
0
0
0
0
10
0
0
0
10
0
0
60
0
0
% F
% Gly:
0
0
0
60
0
0
0
0
0
0
0
0
10
0
0
% G
% His:
0
0
10
0
0
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
0
0
0
0
10
0
0
0
0
60
60
0
10
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
20
80
10
10
10
60
20
10
70
0
10
10
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
10
0
0
0
60
0
0
0
0
0
0
0
0
% N
% Pro:
10
10
10
0
10
0
0
0
0
60
10
0
0
0
0
% P
% Gln:
0
0
0
10
10
10
10
0
0
0
0
0
0
0
10
% Q
% Arg:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
70
20
0
0
0
0
10
10
% S
% Thr:
0
0
0
10
0
0
0
0
10
0
10
0
0
10
20
% T
% Val:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% V
% Trp:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
0
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _