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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM135A
All Species:
12.12
Human Site:
T1189
Identified Species:
29.63
UniProt:
Q9P2D6
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P2D6
NP_001099001.1
1515
169840
T1189
S
S
T
S
Y
N
F
T
S
S
I
S
W
Y
E
Chimpanzee
Pan troglodytes
XP_001138203
1515
169815
T1189
S
S
T
S
Y
N
F
T
S
S
I
S
W
Y
E
Rhesus Macaque
Macaca mulatta
XP_001089896
1308
144316
F995
E
E
V
S
E
R
M
F
S
F
Y
Q
A
K
E
Dog
Lupus familis
XP_853259
1517
169912
A1191
C
S
T
S
Y
N
F
A
S
S
V
S
W
Y
E
Cat
Felis silvestris
Mouse
Mus musculus
Q6NS59
1506
166838
S1181
S
I
S
Y
N
F
S
S
S
T
S
W
Y
E
N
Rat
Rattus norvegicus
NP_001128069
1507
167117
S1182
S
I
S
Y
N
F
T
S
S
T
S
W
Y
E
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510578
1506
167802
T1180
S
S
I
S
Y
S
S
T
S
S
L
S
W
Y
E
Chicken
Gallus gallus
XP_419888
1500
166663
A1174
G
S
T
S
Y
S
S
A
L
P
V
S
W
Y
E
Frog
Xenopus laevis
Q641I1
1376
154423
R1063
T
D
E
E
S
N
E
R
M
L
S
F
H
Q
A
Zebra Danio
Brachydanio rerio
NP_001139066
1338
148314
Q1025
Y
K
S
A
P
T
A
Q
M
T
A
F
V
Q
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
35.8
91
N.A.
83.8
81.6
N.A.
76
71.8
39.4
52.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
53.2
95.3
N.A.
91.2
89.4
N.A.
85.1
82.5
56.9
67.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
20
80
N.A.
13.3
13.3
N.A.
73.3
53.3
6.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
20
86.6
N.A.
40
40
N.A.
86.6
66.6
13.3
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
10
20
0
0
10
0
10
0
20
% A
% Cys:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
10
10
10
10
10
0
10
0
0
0
0
0
0
20
60
% E
% Phe:
0
0
0
0
0
20
30
10
0
10
0
20
0
0
0
% F
% Gly:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
20
10
0
0
0
0
0
0
0
20
0
0
0
0
% I
% Lys:
0
10
0
0
0
0
0
0
0
0
0
0
0
10
0
% K
% Leu:
0
0
0
0
0
0
0
0
10
10
10
0
0
0
0
% L
% Met:
0
0
0
0
0
0
10
0
20
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
20
40
0
0
0
0
0
0
0
0
20
% N
% Pro:
0
0
0
0
10
0
0
0
0
10
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
10
0
0
0
10
0
20
0
% Q
% Arg:
0
0
0
0
0
10
0
10
0
0
0
0
0
0
0
% R
% Ser:
50
50
30
60
10
20
30
20
70
40
30
50
0
0
0
% S
% Thr:
10
0
40
0
0
10
10
30
0
30
0
0
0
0
0
% T
% Val:
0
0
10
0
0
0
0
0
0
0
20
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
20
50
0
0
% W
% Tyr:
10
0
0
20
50
0
0
0
0
0
10
0
20
50
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _