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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIAA1409 All Species: 1.82
Human Site: S1727 Identified Species: 4
UniProt: Q9P2D8 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P2D8 NP_065869.3 2635 295312 S1727 P M D A E G S S K P E E L P E
Chimpanzee Pan troglodytes XP_001150811 2458 275453 L1600 E G E K P G E L M P S S G A K
Rhesus Macaque Macaca mulatta XP_001095032 2458 275533 L1600 E G E K P G E L M P S S G A K
Dog Lupus familis XP_547957 1443 160072 S589 P G E L M P S S G T K T V L L
Cat Felis silvestris
Mouse Mus musculus Q0KK59 2596 290721 D1712 H Q S A S N E D S T I A A L D
Rat Rattus norvegicus XP_002726807 2591 290355 V1714 V S N E D S T V T A L D D L M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510923 2564 288167 D1705 P L R I V E S D E E E E F A T
Chicken Gallus gallus XP_421335 2458 276086 G1600 V E E I R P S G A I P S P N V
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650795 3028 333679 A2081 S A P A A I Q A S S S A A A S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_497814 2082 234872 R1228 V D M E N P E R H T V Y L V V
Sea Urchin Strong. purpuratus XP_001185893 2211 245811 E1357 Q H Q E L E L E P E M L F V S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 92.5 92.4 48.7 N.A. 94.3 94.1 N.A. 87.7 83.9 N.A. N.A. N.A. 28.3 N.A. 25.8 27.8
Protein Similarity: 100 93 92.8 51.7 N.A. 96 96 N.A. 90.9 87.9 N.A. N.A. N.A. 45.4 N.A. 43.7 45.3
P-Site Identity: 100 13.3 13.3 20 N.A. 6.6 0 N.A. 26.6 6.6 N.A. N.A. N.A. 6.6 N.A. 6.6 0
P-Site Similarity: 100 26.6 26.6 40 N.A. 13.3 26.6 N.A. 40 13.3 N.A. N.A. N.A. 13.3 N.A. 6.6 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 28 10 0 0 10 10 10 0 19 19 37 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 10 0 10 0 0 19 0 0 0 10 10 0 10 % D
% Glu: 19 10 37 28 10 19 37 10 10 19 19 19 0 0 10 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 19 0 0 % F
% Gly: 0 28 0 0 0 28 0 10 10 0 0 0 19 0 0 % G
% His: 10 10 0 0 0 0 0 0 10 0 0 0 0 0 0 % H
% Ile: 0 0 0 19 0 10 0 0 0 10 10 0 0 0 0 % I
% Lys: 0 0 0 19 0 0 0 0 10 0 10 0 0 0 19 % K
% Leu: 0 10 0 10 10 0 10 19 0 0 10 10 19 28 10 % L
% Met: 0 10 10 0 10 0 0 0 19 0 10 0 0 0 10 % M
% Asn: 0 0 10 0 10 10 0 0 0 0 0 0 0 10 0 % N
% Pro: 28 0 10 0 19 28 0 0 10 28 10 0 10 10 0 % P
% Gln: 10 10 10 0 0 0 10 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 10 0 10 0 0 10 0 0 0 0 0 0 0 % R
% Ser: 10 10 10 0 10 10 37 19 19 10 28 28 0 0 19 % S
% Thr: 0 0 0 0 0 0 10 0 10 28 0 10 0 0 10 % T
% Val: 28 0 0 0 10 0 0 10 0 0 10 0 10 19 19 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _