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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF17 All Species: 10.61
Human Site: Y486 Identified Species: 19.44
UniProt: Q9P2E2 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P2E2 NP_001116291.1 1029 115114 Y486 E F A S S A E Y P P A F Q Y E
Chimpanzee Pan troglodytes XP_513170 1224 134999 Y681 E F A S S S E Y P P A F Q Y E
Rhesus Macaque Macaca mulatta XP_001109013 1004 111859 Y462 E F A T S S E Y P P A F Q Y E
Dog Lupus familis XP_850988 765 87086 N308 L Q D S L G G N A K T V M V A
Cat Felis silvestris
Mouse Mus musculus Q99PW8 1038 116354 P486 R A E L A S G P E Y S P P L Q
Rat Rattus norvegicus O55165 796 89797 I339 L G G N A K T I M V A T L G P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001012852 739 84717 L282 L G N V I S A L V D G K S T H
Frog Xenopus laevis Q498L9 1387 158540 Y517 H H P R V A K Y A L E N H S L
Zebra Danio Brachydanio rerio XP_001919146 823 92211 G366 K L R A L I S G Q L G S G N L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P46867 784 88189 N327 N I G P S N Y N Y N E T L T T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P46873 699 78760 T242 G S E R Q S K T G A T G D R L
Sea Urchin Strong. purpuratus P46871 742 84184 K285 I S A L V D G K S S H I P Y R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P48467 928 102392 E462 E S I A A A A E R Q L R E T K
Conservation
Percent
Protein Identity: 100 83.1 87.5 34.1 N.A. 80.1 26.8 N.A. N.A. 33.8 25.8 50.6 N.A. 31.4 N.A. 37.9 34.1
Protein Similarity: 100 83.6 90.4 49.5 N.A. 86.8 42.5 N.A. N.A. 49.7 43.2 64.7 N.A. 48 N.A. 51.1 48.9
P-Site Identity: 100 93.3 86.6 6.6 N.A. 0 6.6 N.A. N.A. 0 13.3 0 N.A. 6.6 N.A. 0 13.3
P-Site Similarity: 100 100 100 6.6 N.A. 26.6 20 N.A. N.A. 6.6 20 13.3 N.A. 6.6 N.A. 13.3 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 28.3
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 46.9
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 40
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 31 16 24 24 16 0 16 8 31 0 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 8 0 0 8 0 0 0 8 0 0 8 0 0 % D
% Glu: 31 0 16 0 0 0 24 8 8 0 16 0 8 0 24 % E
% Phe: 0 24 0 0 0 0 0 0 0 0 0 24 0 0 0 % F
% Gly: 8 16 16 0 0 8 24 8 8 0 16 8 8 8 0 % G
% His: 8 8 0 0 0 0 0 0 0 0 8 0 8 0 8 % H
% Ile: 8 8 8 0 8 8 0 8 0 0 0 8 0 0 0 % I
% Lys: 8 0 0 0 0 8 16 8 0 8 0 8 0 0 8 % K
% Leu: 24 8 0 16 16 0 0 8 0 16 8 0 16 8 24 % L
% Met: 0 0 0 0 0 0 0 0 8 0 0 0 8 0 0 % M
% Asn: 8 0 8 8 0 8 0 16 0 8 0 8 0 8 0 % N
% Pro: 0 0 8 8 0 0 0 8 24 24 0 8 16 0 8 % P
% Gln: 0 8 0 0 8 0 0 0 8 8 0 0 24 0 8 % Q
% Arg: 8 0 8 16 0 0 0 0 8 0 0 8 0 8 8 % R
% Ser: 0 24 0 24 31 39 8 0 8 8 8 8 8 8 0 % S
% Thr: 0 0 0 8 0 0 8 8 0 0 16 16 0 24 8 % T
% Val: 0 0 0 8 16 0 0 0 8 8 0 8 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 8 31 8 8 0 0 0 31 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _