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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KLHL14
All Species:
13.64
Human Site:
T435
Identified Species:
37.5
UniProt:
Q9P2G3
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P2G3
NP_065856.1
628
70714
T435
V
I
G
G
R
N
E
T
G
Y
L
S
S
V
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001100839
629
70823
T436
V
I
G
G
R
N
E
T
G
Y
L
S
S
V
E
Dog
Lupus familis
XP_855391
781
86730
T588
V
I
G
G
R
N
E
T
G
Y
L
S
S
V
E
Cat
Felis silvestris
Mouse
Mus musculus
Q80TF4
654
73768
A451
A
V
G
G
R
N
A
A
G
E
L
P
T
V
E
Rat
Rattus norvegicus
Q66HD2
613
69917
N406
A
V
G
G
R
N
E
N
G
A
L
S
S
V
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515198
558
62881
V371
E
T
G
Y
L
S
S
V
E
R
Y
N
L
E
S
Chicken
Gallus gallus
Q5F3N5
622
69679
T429
V
I
G
G
R
N
E
T
G
Y
L
S
S
V
E
Frog
Xenopus laevis
Q6NRH0
564
63190
I377
A
T
T
L
G
D
M
I
Y
V
S
G
G
F
D
Zebra Danio
Brachydanio rerio
Q6Q7X9
635
70787
D431
A
V
G
G
R
N
S
D
G
C
Q
A
S
V
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.8
79.9
N.A.
33.3
27.5
N.A.
82.9
95
24
33.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
99.8
80
N.A.
49.8
47.6
N.A.
84.5
95.8
43.9
51.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
100
100
N.A.
53.3
73.3
N.A.
6.6
100
0
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
66.6
80
N.A.
20
100
13.3
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
45
0
0
0
0
0
12
12
0
12
0
12
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
12
0
12
0
0
0
0
0
0
12
% D
% Glu:
12
0
0
0
0
0
56
0
12
12
0
0
0
12
78
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% F
% Gly:
0
0
89
78
12
0
0
0
78
0
0
12
12
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
45
0
0
0
0
0
12
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
12
12
0
0
0
0
0
67
0
12
0
0
% L
% Met:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
78
0
12
0
0
0
12
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% Q
% Arg:
0
0
0
0
78
0
0
0
0
12
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
12
23
0
0
0
12
56
67
0
12
% S
% Thr:
0
23
12
0
0
0
0
45
0
0
0
0
12
0
0
% T
% Val:
45
34
0
0
0
0
0
12
0
12
0
0
0
78
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
12
0
0
0
0
12
45
12
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _