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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP35
All Species:
8.48
Human Site:
S230
Identified Species:
15.56
UniProt:
Q9P2H5
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P2H5
NP_065849.1
1017
113348
S230
C
E
E
E
P
P
S
S
A
L
A
S
V
V
Q
Chimpanzee
Pan troglodytes
XP_517457
1042
116629
V235
D
A
S
F
E
P
S
V
A
L
A
S
L
V
Q
Rhesus Macaque
Macaca mulatta
XP_001092815
1041
116552
V235
D
A
S
F
E
P
S
V
A
L
A
S
L
V
Q
Dog
Lupus familis
XP_542286
1072
119038
S296
T
E
E
E
P
P
S
S
A
L
A
S
V
V
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8BW70
1042
116083
V235
D
A
S
F
E
P
S
V
A
L
A
S
L
V
Q
Rat
Rattus norvegicus
XP_238899
1007
111999
S231
T
E
E
E
P
P
S
S
A
L
A
S
V
V
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513216
898
98952
Q106
L
V
Q
H
I
P
L
Q
M
I
T
V
L
I
R
Chicken
Gallus gallus
XP_417222
997
112612
N235
E
E
Q
E
V
P
S
N
A
L
A
S
V
V
Q
Frog
Xenopus laevis
NP_001087645
1037
116290
V235
D
A
S
F
E
P
S
V
S
L
A
S
L
V
Q
Zebra Danio
Brachydanio rerio
XP_001919108
1014
112064
I235
D
P
S
F
E
P
S
I
A
L
A
S
L
V
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610784
852
94928
D98
I
C
E
R
V
I
V
D
L
A
R
L
Q
I
P
Honey Bee
Apis mellifera
XP_395580
833
95824
K105
F
V
M
P
C
D
P
K
K
I
S
E
F
N
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001178896
1119
124137
L229
E
E
S
Q
N
P
S
L
A
L
G
A
L
V
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
38.2
38.7
86.4
N.A.
38.9
88.7
N.A.
34.1
64.6
37
38.6
N.A.
24.4
25.3
N.A.
34.1
Protein Similarity:
100
54.9
55.1
88.3
N.A.
55.7
92.4
N.A.
49.4
76.7
54.6
55.2
N.A.
41.8
44.6
N.A.
50.4
P-Site Identity:
100
53.3
53.3
93.3
N.A.
53.3
93.3
N.A.
6.6
73.3
46.6
53.3
N.A.
6.6
0
N.A.
46.6
P-Site Similarity:
100
60
60
93.3
N.A.
60
93.3
N.A.
40
86.6
60
60
N.A.
13.3
13.3
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
31
0
0
0
0
0
0
70
8
70
8
0
0
0
% A
% Cys:
8
8
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
39
0
0
0
0
8
0
8
0
0
0
0
0
0
8
% D
% Glu:
16
39
31
31
39
0
0
0
0
0
0
8
0
0
0
% E
% Phe:
8
0
0
39
0
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
8
8
0
8
0
16
0
0
0
16
0
% I
% Lys:
0
0
0
0
0
0
0
8
8
0
0
0
0
0
0
% K
% Leu:
8
0
0
0
0
0
8
8
8
77
0
8
54
0
0
% L
% Met:
0
0
8
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
0
8
0
0
0
0
0
8
0
% N
% Pro:
0
8
0
8
24
85
8
0
0
0
0
0
0
0
8
% P
% Gln:
0
0
16
8
0
0
0
8
0
0
0
0
8
0
77
% Q
% Arg:
0
0
0
8
0
0
0
0
0
0
8
0
0
0
8
% R
% Ser:
0
0
47
0
0
0
77
24
8
0
8
70
0
0
0
% S
% Thr:
16
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% T
% Val:
0
16
0
0
16
0
8
31
0
0
0
8
31
77
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _