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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP35
All Species:
13.64
Human Site:
S548
Identified Species:
25
UniProt:
Q9P2H5
Number Species:
12
Phosphosite Substitution
Charge Score:
0.5
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P2H5
NP_065849.1
1017
113348
S548
I
C
Q
K
L
K
Q
S
S
S
P
S
P
P
E
Chimpanzee
Pan troglodytes
XP_517457
1042
116629
E553
Q
A
S
H
K
P
S
E
I
L
E
C
S
E
T
Rhesus Macaque
Macaca mulatta
XP_001092815
1041
116552
E553
Q
S
S
H
K
P
S
E
I
L
E
C
S
E
T
Dog
Lupus familis
XP_542286
1072
119038
S614
I
C
Q
K
L
K
Q
S
S
S
P
S
P
P
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8BW70
1042
116083
E553
Q
S
S
H
K
P
S
E
G
L
D
C
A
E
T
Rat
Rattus norvegicus
XP_238899
1007
111999
S549
I
C
Q
K
L
K
Q
S
S
L
P
S
P
Q
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513216
898
98952
E412
L
S
S
L
K
P
P
E
N
P
G
S
E
E
M
Chicken
Gallus gallus
XP_417222
997
112612
S553
I
Y
Q
K
L
K
E
S
S
L
M
S
Q
A
M
Frog
Xenopus laevis
NP_001087645
1037
116290
D552
L
C
S
K
L
P
S
D
A
P
V
T
D
C
S
Zebra Danio
Brachydanio rerio
XP_001919108
1014
112064
P553
L
Q
T
A
S
P
K
P
E
P
A
T
T
S
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610784
852
94928
S383
L
A
M
T
S
D
F
S
R
Q
I
L
L
I
E
Honey Bee
Apis mellifera
XP_395580
833
95824
E390
M
T
K
Q
F
C
Y
E
V
L
M
Y
K
P
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001178896
1119
124137
S548
M
M
K
N
A
A
A
S
I
S
S
S
L
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
38.2
38.7
86.4
N.A.
38.9
88.7
N.A.
34.1
64.6
37
38.6
N.A.
24.4
25.3
N.A.
34.1
Protein Similarity:
100
54.9
55.1
88.3
N.A.
55.7
92.4
N.A.
49.4
76.7
54.6
55.2
N.A.
41.8
44.6
N.A.
50.4
P-Site Identity:
100
0
0
100
N.A.
0
86.6
N.A.
6.6
53.3
20
0
N.A.
13.3
6.6
N.A.
20
P-Site Similarity:
100
0
0
100
N.A.
0
86.6
N.A.
20
60
40
20
N.A.
20
26.6
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
0
8
8
8
8
0
8
0
8
0
8
8
0
% A
% Cys:
0
31
0
0
0
8
0
0
0
0
0
24
0
8
0
% C
% Asp:
0
0
0
0
0
8
0
8
0
0
8
0
8
0
0
% D
% Glu:
0
0
0
0
0
0
8
39
8
0
16
0
8
31
31
% E
% Phe:
0
0
0
0
8
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
8
0
8
0
0
0
0
% G
% His:
0
0
0
24
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
31
0
0
0
0
0
0
0
24
0
8
0
0
8
0
% I
% Lys:
0
0
16
39
31
31
8
0
0
0
0
0
8
0
0
% K
% Leu:
31
0
0
8
39
0
0
0
0
47
0
8
16
0
8
% L
% Met:
16
8
8
0
0
0
0
0
0
0
16
0
0
0
16
% M
% Asn:
0
0
0
8
0
0
0
0
8
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
47
8
8
0
24
24
0
24
24
8
% P
% Gln:
24
8
31
8
0
0
24
0
0
8
0
0
8
8
0
% Q
% Arg:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% R
% Ser:
0
24
39
0
16
0
31
47
31
24
8
47
16
16
16
% S
% Thr:
0
8
8
8
0
0
0
0
0
0
0
16
8
0
24
% T
% Val:
0
0
0
0
0
0
0
0
8
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
8
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _