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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: USP35 All Species: 13.64
Human Site: S548 Identified Species: 25
UniProt: Q9P2H5 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.5
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P2H5 NP_065849.1 1017 113348 S548 I C Q K L K Q S S S P S P P E
Chimpanzee Pan troglodytes XP_517457 1042 116629 E553 Q A S H K P S E I L E C S E T
Rhesus Macaque Macaca mulatta XP_001092815 1041 116552 E553 Q S S H K P S E I L E C S E T
Dog Lupus familis XP_542286 1072 119038 S614 I C Q K L K Q S S S P S P P E
Cat Felis silvestris
Mouse Mus musculus Q8BW70 1042 116083 E553 Q S S H K P S E G L D C A E T
Rat Rattus norvegicus XP_238899 1007 111999 S549 I C Q K L K Q S S L P S P Q E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513216 898 98952 E412 L S S L K P P E N P G S E E M
Chicken Gallus gallus XP_417222 997 112612 S553 I Y Q K L K E S S L M S Q A M
Frog Xenopus laevis NP_001087645 1037 116290 D552 L C S K L P S D A P V T D C S
Zebra Danio Brachydanio rerio XP_001919108 1014 112064 P553 L Q T A S P K P E P A T T S P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610784 852 94928 S383 L A M T S D F S R Q I L L I E
Honey Bee Apis mellifera XP_395580 833 95824 E390 M T K Q F C Y E V L M Y K P L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001178896 1119 124137 S548 M M K N A A A S I S S S L S S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 38.2 38.7 86.4 N.A. 38.9 88.7 N.A. 34.1 64.6 37 38.6 N.A. 24.4 25.3 N.A. 34.1
Protein Similarity: 100 54.9 55.1 88.3 N.A. 55.7 92.4 N.A. 49.4 76.7 54.6 55.2 N.A. 41.8 44.6 N.A. 50.4
P-Site Identity: 100 0 0 100 N.A. 0 86.6 N.A. 6.6 53.3 20 0 N.A. 13.3 6.6 N.A. 20
P-Site Similarity: 100 0 0 100 N.A. 0 86.6 N.A. 20 60 40 20 N.A. 20 26.6 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 16 0 8 8 8 8 0 8 0 8 0 8 8 0 % A
% Cys: 0 31 0 0 0 8 0 0 0 0 0 24 0 8 0 % C
% Asp: 0 0 0 0 0 8 0 8 0 0 8 0 8 0 0 % D
% Glu: 0 0 0 0 0 0 8 39 8 0 16 0 8 31 31 % E
% Phe: 0 0 0 0 8 0 8 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 8 0 8 0 0 0 0 % G
% His: 0 0 0 24 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 31 0 0 0 0 0 0 0 24 0 8 0 0 8 0 % I
% Lys: 0 0 16 39 31 31 8 0 0 0 0 0 8 0 0 % K
% Leu: 31 0 0 8 39 0 0 0 0 47 0 8 16 0 8 % L
% Met: 16 8 8 0 0 0 0 0 0 0 16 0 0 0 16 % M
% Asn: 0 0 0 8 0 0 0 0 8 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 47 8 8 0 24 24 0 24 24 8 % P
% Gln: 24 8 31 8 0 0 24 0 0 8 0 0 8 8 0 % Q
% Arg: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % R
% Ser: 0 24 39 0 16 0 31 47 31 24 8 47 16 16 16 % S
% Thr: 0 8 8 8 0 0 0 0 0 0 0 16 8 0 24 % T
% Val: 0 0 0 0 0 0 0 0 8 0 8 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 0 0 8 0 0 0 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _