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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: USP35 All Species: 13.94
Human Site: S630 Identified Species: 25.56
UniProt: Q9P2H5 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P2H5 NP_065849.1 1017 113348 S630 R E L P P P T S A Q G P G R V
Chimpanzee Pan troglodytes XP_517457 1042 116629 S639 Q D P A S S P S I Q D G G L M
Rhesus Macaque Macaca mulatta XP_001092815 1041 116552 S638 Q D P A S S P S T Q D G G L M
Dog Lupus familis XP_542286 1072 119038 Q696 Q D P P P P S Q A Q V P S R V
Cat Felis silvestris
Mouse Mus musculus Q8BW70 1042 116083 S639 Q D T A S L P S A Q D D G L M
Rat Rattus norvegicus XP_238899 1007 111999 R631 Q E L T L A P R A P G A Q R Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513216 898 98952 S493 E N V S S Q G S A R S P G V Q
Chicken Gallus gallus XP_417222 997 112612 T635 Q F I E P P K T P S Q P T G S
Frog Xenopus laevis NP_001087645 1037 116290 T637 V D K P V Q S T L D S P K Q K
Zebra Danio Brachydanio rerio XP_001919108 1014 112064 T636 M S Q P R G P T N E H K S S S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610784 852 94928 T467 H S V G P P K T G R E V D D V
Honey Bee Apis mellifera XP_395580 833 95824 N471 S T I N G E A N T N L K Y K D
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001178896 1119 124137 A630 D E L Y L P T A S D T A C C S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 38.2 38.7 86.4 N.A. 38.9 88.7 N.A. 34.1 64.6 37 38.6 N.A. 24.4 25.3 N.A. 34.1
Protein Similarity: 100 54.9 55.1 88.3 N.A. 55.7 92.4 N.A. 49.4 76.7 54.6 55.2 N.A. 41.8 44.6 N.A. 50.4
P-Site Identity: 100 20 20 53.3 N.A. 26.6 33.3 N.A. 26.6 20 13.3 6.6 N.A. 20 0 N.A. 26.6
P-Site Similarity: 100 40 40 73.3 N.A. 46.6 40 N.A. 40 40 40 20 N.A. 40 20 N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 24 0 8 8 8 39 0 0 16 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 8 8 0 % C
% Asp: 8 39 0 0 0 0 0 0 0 16 24 8 8 8 8 % D
% Glu: 8 24 0 8 0 8 0 0 0 8 8 0 0 0 0 % E
% Phe: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 8 8 8 8 0 8 0 16 16 39 8 0 % G
% His: 8 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % H
% Ile: 0 0 16 0 0 0 0 0 8 0 0 0 0 0 0 % I
% Lys: 0 0 8 0 0 0 16 0 0 0 0 16 8 8 8 % K
% Leu: 0 0 24 0 16 8 0 0 8 0 8 0 0 24 0 % L
% Met: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 24 % M
% Asn: 0 8 0 8 0 0 0 8 8 8 0 0 0 0 0 % N
% Pro: 0 0 24 31 31 39 39 0 8 8 0 39 0 0 0 % P
% Gln: 47 0 8 0 0 16 0 8 0 39 8 0 8 8 16 % Q
% Arg: 8 0 0 0 8 0 0 8 0 16 0 0 0 24 0 % R
% Ser: 8 16 0 8 31 16 16 39 8 8 16 0 16 8 24 % S
% Thr: 0 8 8 8 0 0 16 31 16 0 8 0 8 0 0 % T
% Val: 8 0 16 0 8 0 0 0 0 0 8 8 0 8 24 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 0 0 0 0 0 0 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _