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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP35
All Species:
7.27
Human Site:
S698
Identified Species:
13.33
UniProt:
Q9P2H5
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P2H5
NP_065849.1
1017
113348
S698
E
V
G
E
E
E
E
S
T
R
G
E
G
E
R
Chimpanzee
Pan troglodytes
XP_517457
1042
116629
S712
D
V
P
Q
K
P
G
S
E
T
T
P
S
V
T
Rhesus Macaque
Macaca mulatta
XP_001092815
1041
116552
T713
P
Q
K
P
G
G
E
T
T
P
S
V
T
D
L
Dog
Lupus familis
XP_542286
1072
119038
E761
R
E
E
E
E
E
E
E
E
K
K
E
K
E
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8BW70
1042
116083
N709
I
S
K
D
V
P
Q
N
P
G
G
E
S
T
T
Rat
Rattus norvegicus
XP_238899
1007
111999
E697
G
P
R
E
E
E
K
E
E
G
E
E
K
D
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513216
898
98952
S558
E
D
P
Y
R
F
Q
S
N
R
E
A
S
Q
K
Chicken
Gallus gallus
XP_417222
997
112612
D702
E
Q
T
C
A
P
K
D
S
R
S
V
P
D
L
Frog
Xenopus laevis
NP_001087645
1037
116290
M705
N
A
V
E
S
D
N
M
S
A
Q
N
N
R
R
Zebra Danio
Brachydanio rerio
XP_001919108
1014
112064
C700
E
I
L
E
N
E
N
C
Y
F
C
E
R
C
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610784
852
94928
Q534
Q
Q
G
Q
Q
V
D
Q
A
K
P
P
S
T
I
Honey Bee
Apis mellifera
XP_395580
833
95824
S537
Q
E
L
S
D
S
H
S
D
S
T
D
S
G
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001178896
1119
124137
S694
C
L
N
C
G
T
V
S
S
R
K
E
T
F
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
38.2
38.7
86.4
N.A.
38.9
88.7
N.A.
34.1
64.6
37
38.6
N.A.
24.4
25.3
N.A.
34.1
Protein Similarity:
100
54.9
55.1
88.3
N.A.
55.7
92.4
N.A.
49.4
76.7
54.6
55.2
N.A.
41.8
44.6
N.A.
50.4
P-Site Identity:
100
13.3
13.3
40
N.A.
13.3
26.6
N.A.
20
13.3
13.3
26.6
N.A.
6.6
6.6
N.A.
20
P-Site Similarity:
100
33.3
26.6
53.3
N.A.
33.3
46.6
N.A.
40
33.3
26.6
33.3
N.A.
40
26.6
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
8
0
0
0
8
8
0
8
0
0
8
% A
% Cys:
8
0
0
16
0
0
0
8
0
0
8
0
0
8
0
% C
% Asp:
8
8
0
8
8
8
8
8
8
0
0
8
0
24
0
% D
% Glu:
31
16
8
39
24
31
24
16
24
0
16
47
0
16
0
% E
% Phe:
0
0
0
0
0
8
0
0
0
8
0
0
0
8
8
% F
% Gly:
8
0
16
0
16
8
8
0
0
16
16
0
8
8
0
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
16
% I
% Lys:
0
0
16
0
8
0
16
0
0
16
16
0
16
0
24
% K
% Leu:
0
8
16
0
0
0
0
0
0
0
0
0
0
0
16
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
8
0
8
0
8
0
16
8
8
0
0
8
8
0
0
% N
% Pro:
8
8
16
8
0
24
0
0
8
8
8
16
8
0
0
% P
% Gln:
16
24
0
16
8
0
16
8
0
0
8
0
0
8
0
% Q
% Arg:
8
0
8
0
8
0
0
0
0
31
0
0
8
8
16
% R
% Ser:
0
8
0
8
8
8
0
39
24
8
16
0
39
0
0
% S
% Thr:
0
0
8
0
0
8
0
8
16
8
16
0
16
16
16
% T
% Val:
0
16
8
0
8
8
8
0
0
0
0
16
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _