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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP35
All Species:
7.58
Human Site:
S747
Identified Species:
13.89
UniProt:
Q9P2H5
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P2H5
NP_065849.1
1017
113348
S747
H
P
D
A
A
I
P
S
G
E
R
T
C
G
S
Chimpanzee
Pan troglodytes
XP_517457
1042
116629
T764
E
P
E
Y
L
I
L
T
L
L
R
F
S
Y
D
Rhesus Macaque
Macaca mulatta
XP_001092815
1041
116552
T763
E
P
E
Y
L
I
L
T
L
L
R
F
S
Y
D
Dog
Lupus familis
XP_542286
1072
119038
H802
D
S
S
G
Q
G
S
H
R
G
A
A
P
A
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8BW70
1042
116083
T764
E
P
E
Y
L
I
L
T
L
L
R
F
S
Y
D
Rat
Rattus norvegicus
XP_238899
1007
111999
P738
R
K
D
A
A
T
P
P
R
E
Q
A
C
G
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513216
898
98952
T620
E
P
E
Y
L
I
L
T
L
L
R
F
S
Y
D
Chicken
Gallus gallus
XP_417222
997
112612
T743
A
E
K
V
A
E
L
T
E
G
P
H
Y
L
I
Frog
Xenopus laevis
NP_001087645
1037
116290
N747
E
K
C
A
S
L
Q
N
A
E
K
T
M
Q
I
Zebra Danio
Brachydanio rerio
XP_001919108
1014
112064
R741
Y
D
A
T
C
H
V
R
R
K
I
L
D
N
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610784
852
94928
P576
R
E
L
Q
L
S
F
P
D
D
K
E
D
C
G
Honey Bee
Apis mellifera
XP_395580
833
95824
T578
Y
Q
C
A
Q
C
D
T
S
S
D
N
T
D
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001178896
1119
124137
G771
R
S
T
S
E
A
Q
G
V
A
G
S
N
S
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
38.2
38.7
86.4
N.A.
38.9
88.7
N.A.
34.1
64.6
37
38.6
N.A.
24.4
25.3
N.A.
34.1
Protein Similarity:
100
54.9
55.1
88.3
N.A.
55.7
92.4
N.A.
49.4
76.7
54.6
55.2
N.A.
41.8
44.6
N.A.
50.4
P-Site Identity:
100
20
20
0
N.A.
20
46.6
N.A.
20
6.6
20
0
N.A.
0
6.6
N.A.
0
P-Site Similarity:
100
33.3
33.3
6.6
N.A.
33.3
53.3
N.A.
33.3
13.3
46.6
13.3
N.A.
13.3
20
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
31
24
8
0
0
8
8
8
16
0
8
8
% A
% Cys:
0
0
16
0
8
8
0
0
0
0
0
0
16
8
0
% C
% Asp:
8
8
16
0
0
0
8
0
8
8
8
0
16
8
31
% D
% Glu:
39
16
31
0
8
8
0
0
8
24
0
8
0
0
8
% E
% Phe:
0
0
0
0
0
0
8
0
0
0
0
31
0
0
0
% F
% Gly:
0
0
0
8
0
8
0
8
8
16
8
0
0
16
8
% G
% His:
8
0
0
0
0
8
0
8
0
0
0
8
0
0
0
% H
% Ile:
0
0
0
0
0
39
0
0
0
0
8
0
0
0
16
% I
% Lys:
0
16
8
0
0
0
0
0
0
8
16
0
0
0
8
% K
% Leu:
0
0
8
0
39
8
39
0
31
31
0
8
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
0
8
8
8
0
% N
% Pro:
0
39
0
0
0
0
16
16
0
0
8
0
8
0
8
% P
% Gln:
0
8
0
8
16
0
16
0
0
0
8
0
0
8
0
% Q
% Arg:
24
0
0
0
0
0
0
8
24
0
39
0
0
0
0
% R
% Ser:
0
16
8
8
8
8
8
8
8
8
0
8
31
8
8
% S
% Thr:
0
0
8
8
0
8
0
47
0
0
0
16
8
0
0
% T
% Val:
0
0
0
8
0
0
8
0
8
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
16
0
0
31
0
0
0
0
0
0
0
0
8
31
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _