KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP35
All Species:
31.21
Human Site:
T418
Identified Species:
57.22
UniProt:
Q9P2H5
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P2H5
NP_065849.1
1017
113348
T418
L
L
G
Q
D
A
W
T
S
Q
K
S
E
L
A
Chimpanzee
Pan troglodytes
XP_517457
1042
116629
T423
I
L
N
Q
S
A
W
T
S
Q
S
N
S
L
A
Rhesus Macaque
Macaca mulatta
XP_001092815
1041
116552
T423
I
L
N
Q
S
A
W
T
S
Q
S
N
S
L
A
Dog
Lupus familis
XP_542286
1072
119038
T484
L
L
G
Q
D
A
W
T
S
Q
K
S
E
L
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8BW70
1042
116083
T423
I
L
N
Q
S
A
W
T
S
Q
S
N
A
L
A
Rat
Rattus norvegicus
XP_238899
1007
111999
T419
L
L
G
Q
D
A
W
T
S
Q
K
S
E
L
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513216
898
98952
T282
I
L
N
Q
S
A
W
T
S
Q
S
N
S
L
A
Chicken
Gallus gallus
XP_417222
997
112612
T423
L
L
G
Q
N
A
W
T
S
Q
K
N
E
L
A
Frog
Xenopus laevis
NP_001087645
1037
116290
W422
L
T
L
N
Q
S
A
W
T
S
Q
S
S
T
L
Zebra Danio
Brachydanio rerio
XP_001919108
1014
112064
T423
V
L
N
Q
S
A
W
T
S
Q
S
N
S
F
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610784
852
94928
V253
L
R
Q
K
A
A
P
V
V
F
H
M
L
S
T
Honey Bee
Apis mellifera
XP_395580
833
95824
I260
A
S
T
I
I
F
Y
I
L
K
R
Q
G
S
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001178896
1119
124137
S418
L
K
Q
S
A
W
T
S
Q
K
G
G
L
G
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
38.2
38.7
86.4
N.A.
38.9
88.7
N.A.
34.1
64.6
37
38.6
N.A.
24.4
25.3
N.A.
34.1
Protein Similarity:
100
54.9
55.1
88.3
N.A.
55.7
92.4
N.A.
49.4
76.7
54.6
55.2
N.A.
41.8
44.6
N.A.
50.4
P-Site Identity:
100
60
60
100
N.A.
60
100
N.A.
60
86.6
13.3
53.3
N.A.
13.3
0
N.A.
13.3
P-Site Similarity:
100
73.3
73.3
100
N.A.
73.3
100
N.A.
73.3
100
33.3
66.6
N.A.
20
20
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
16
77
8
0
0
0
0
0
8
0
77
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
24
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
31
0
0
% E
% Phe:
0
0
0
0
0
8
0
0
0
8
0
0
0
8
0
% F
% Gly:
0
0
31
0
0
0
0
0
0
0
8
8
8
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
31
0
0
8
8
0
0
8
0
0
0
0
0
0
0
% I
% Lys:
0
8
0
8
0
0
0
0
0
16
31
0
0
0
0
% K
% Leu:
54
70
8
0
0
0
0
0
8
0
0
0
16
62
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
39
8
8
0
0
0
0
0
0
47
0
0
0
% N
% Pro:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
8
% P
% Gln:
0
0
16
70
8
0
0
0
8
70
8
8
0
0
0
% Q
% Arg:
0
8
0
0
0
0
0
0
0
0
8
0
0
0
0
% R
% Ser:
0
8
0
8
39
8
0
8
70
8
39
31
39
16
0
% S
% Thr:
0
8
8
0
0
0
8
70
8
0
0
0
0
8
8
% T
% Val:
8
0
0
0
0
0
0
8
8
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
8
70
8
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _