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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP35
All Species:
8.48
Human Site:
T621
Identified Species:
15.56
UniProt:
Q9P2H5
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P2H5
NP_065849.1
1017
113348
T621
M
R
P
T
E
D
I
T
A
R
E
L
P
P
P
Chimpanzee
Pan troglodytes
XP_517457
1042
116629
S630
S
S
S
L
E
N
M
S
V
Q
D
P
A
S
S
Rhesus Macaque
Macaca mulatta
XP_001092815
1041
116552
S629
P
S
S
L
E
N
M
S
F
Q
D
P
A
S
S
Dog
Lupus familis
XP_542286
1072
119038
G687
M
L
P
A
E
D
V
G
V
Q
D
P
P
P
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8BW70
1042
116083
S630
S
P
S
V
E
D
L
S
F
Q
D
T
A
S
L
Rat
Rattus norvegicus
XP_238899
1007
111999
R622
M
L
P
T
E
D
V
R
A
Q
E
L
T
L
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513216
898
98952
A484
L
A
F
C
P
S
P
A
A
E
N
V
S
S
Q
Chicken
Gallus gallus
XP_417222
997
112612
G626
V
L
P
V
E
E
I
G
P
Q
F
I
E
P
P
Frog
Xenopus laevis
NP_001087645
1037
116290
T628
L
S
L
A
F
C
P
T
L
V
D
K
P
V
Q
Zebra Danio
Brachydanio rerio
XP_001919108
1014
112064
P627
D
L
S
L
A
F
C
P
S
M
S
Q
P
R
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610784
852
94928
T458
E
I
N
S
S
S
V
T
G
H
S
V
G
P
P
Honey Bee
Apis mellifera
XP_395580
833
95824
K462
D
L
L
H
E
Q
E
K
S
S
T
I
N
G
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001178896
1119
124137
P621
S
N
M
P
V
C
H
P
T
D
E
L
Y
L
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
38.2
38.7
86.4
N.A.
38.9
88.7
N.A.
34.1
64.6
37
38.6
N.A.
24.4
25.3
N.A.
34.1
Protein Similarity:
100
54.9
55.1
88.3
N.A.
55.7
92.4
N.A.
49.4
76.7
54.6
55.2
N.A.
41.8
44.6
N.A.
50.4
P-Site Identity:
100
6.6
6.6
46.6
N.A.
13.3
53.3
N.A.
6.6
33.3
13.3
6.6
N.A.
20
6.6
N.A.
20
P-Site Similarity:
100
40
40
66.6
N.A.
40
66.6
N.A.
20
60
26.6
13.3
N.A.
40
20
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
16
8
0
0
8
24
0
0
0
24
0
8
% A
% Cys:
0
0
0
8
0
16
8
0
0
0
0
0
0
0
0
% C
% Asp:
16
0
0
0
0
31
0
0
0
8
39
0
0
0
0
% D
% Glu:
8
0
0
0
62
8
8
0
0
8
24
0
8
0
8
% E
% Phe:
0
0
8
0
8
8
0
0
16
0
8
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
16
8
0
0
0
8
8
8
% G
% His:
0
0
0
8
0
0
8
0
0
8
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
0
16
0
0
0
0
16
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
8
0
0
0
8
0
0
0
% K
% Leu:
16
39
16
24
0
0
8
0
8
0
0
24
0
16
8
% L
% Met:
24
0
8
0
0
0
16
0
0
8
0
0
0
0
0
% M
% Asn:
0
8
8
0
0
16
0
0
0
0
8
0
8
0
0
% N
% Pro:
8
8
31
8
8
0
16
16
8
0
0
24
31
31
39
% P
% Gln:
0
0
0
0
0
8
0
0
0
47
0
8
0
0
16
% Q
% Arg:
0
8
0
0
0
0
0
8
0
8
0
0
0
8
0
% R
% Ser:
24
24
31
8
8
16
0
24
16
8
16
0
8
31
16
% S
% Thr:
0
0
0
16
0
0
0
24
8
0
8
8
8
0
0
% T
% Val:
8
0
0
16
8
0
24
0
16
8
0
16
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _