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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: USP35 All Species: 7.88
Human Site: T648 Identified Species: 14.44
UniProt: Q9P2H5 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P2H5 NP_065849.1 1017 113348 T648 R Q R K H C I T E D T P P T S
Chimpanzee Pan troglodytes XP_517457 1042 116629 Y660 P S E E P V V Y N P T T A A F
Rhesus Macaque Macaca mulatta XP_001092815 1041 116552 Y659 P S E E P V V Y N P T T A A F
Dog Lupus familis XP_542286 1072 119038 H711 G P R R Q R K H C V T G D A P
Cat Felis silvestris
Mouse Mus musculus Q8BW70 1042 116083 V659 D P E E E P V V Y N P A T A A
Rat Rattus norvegicus XP_238899 1007 111999 A647 K H C I T G D A P R T G L D I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513216 898 98952 P509 G V E S A V L P E E P A P C H
Chicken Gallus gallus XP_417222 997 112612 S652 V R R K P P V S G D P A A Q P
Frog Xenopus laevis NP_001087645 1037 116290 D652 D D D C I E I D I T P S V E A
Zebra Danio Brachydanio rerio XP_001919108 1014 112064 A651 T L G P C Q G A V N G G S E A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610784 852 94928 S484 L L S E D I L S S G V I P Y N
Honey Bee Apis mellifera XP_395580 833 95824 S486 D R E I N D I S S I S E E G A
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001178896 1119 124137 S645 G S S M A M E S S Q S Y G Q A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 38.2 38.7 86.4 N.A. 38.9 88.7 N.A. 34.1 64.6 37 38.6 N.A. 24.4 25.3 N.A. 34.1
Protein Similarity: 100 54.9 55.1 88.3 N.A. 55.7 92.4 N.A. 49.4 76.7 54.6 55.2 N.A. 41.8 44.6 N.A. 50.4
P-Site Identity: 100 6.6 6.6 13.3 N.A. 0 6.6 N.A. 13.3 20 6.6 0 N.A. 6.6 6.6 N.A. 0
P-Site Similarity: 100 20 20 20 N.A. 26.6 13.3 N.A. 26.6 40 13.3 13.3 N.A. 33.3 40 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 16 0 0 16 0 0 0 24 24 31 39 % A
% Cys: 0 0 8 8 8 8 0 0 8 0 0 0 0 8 0 % C
% Asp: 24 8 8 0 8 8 8 8 0 16 0 0 8 8 0 % D
% Glu: 0 0 39 31 8 8 8 0 16 8 0 8 8 16 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 16 % F
% Gly: 24 0 8 0 0 8 8 0 8 8 8 24 8 8 0 % G
% His: 0 8 0 0 8 0 0 8 0 0 0 0 0 0 8 % H
% Ile: 0 0 0 16 8 8 24 0 8 8 0 8 0 0 8 % I
% Lys: 8 0 0 16 0 0 8 0 0 0 0 0 0 0 0 % K
% Leu: 8 16 0 0 0 0 16 0 0 0 0 0 8 0 0 % L
% Met: 0 0 0 8 0 8 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 8 0 0 0 16 16 0 0 0 0 8 % N
% Pro: 16 16 0 8 24 16 0 8 8 16 31 8 24 0 16 % P
% Gln: 0 8 0 0 8 8 0 0 0 8 0 0 0 16 0 % Q
% Arg: 8 16 24 8 0 8 0 0 0 8 0 0 0 0 0 % R
% Ser: 0 24 16 8 0 0 0 31 24 0 16 8 8 0 8 % S
% Thr: 8 0 0 0 8 0 0 8 0 8 39 16 8 8 0 % T
% Val: 8 8 0 0 0 24 31 8 8 8 8 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 16 8 0 0 8 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _