KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP35
All Species:
15.45
Human Site:
Y779
Identified Species:
28.33
UniProt:
Q9P2H5
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.42
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P2H5
NP_065849.1
1017
113348
Y779
K
L
T
A
E
N
R
Y
Y
C
E
S
C
A
S
Chimpanzee
Pan troglodytes
XP_517457
1042
116629
R796
V
L
E
L
P
V
K
R
I
T
S
F
S
S
L
Rhesus Macaque
Macaca mulatta
XP_001092815
1041
116552
R795
V
L
E
L
P
V
K
R
T
T
S
F
S
S
L
Dog
Lupus familis
XP_542286
1072
119038
Y834
R
L
T
A
E
N
R
Y
Y
C
E
P
C
A
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8BW70
1042
116083
R796
V
L
E
L
P
V
K
R
T
A
S
F
S
S
L
Rat
Rattus norvegicus
XP_238899
1007
111999
Y770
R
L
T
A
E
N
R
Y
Y
C
E
S
C
A
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513216
898
98952
R652
V
L
E
L
P
V
K
R
T
T
S
S
L
T
S
Chicken
Gallus gallus
XP_417222
997
112612
P775
I
L
D
N
V
S
I
P
V
V
L
K
L
P
I
Frog
Xenopus laevis
NP_001087645
1037
116290
K779
P
K
C
H
V
R
R
K
I
T
D
N
V
S
I
Zebra Danio
Brachydanio rerio
XP_001919108
1014
112064
S773
S
S
N
V
A
A
S
S
S
T
E
S
P
D
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610784
852
94928
Y608
K
L
D
G
D
N
Q
Y
F
C
P
Q
C
K
K
Honey Bee
Apis mellifera
XP_395580
833
95824
N610
V
S
V
Q
D
L
I
N
Y
Y
L
T
P
E
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001178896
1119
124137
Y803
L
L
V
K
D
N
R
Y
H
C
D
K
C
Q
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
38.2
38.7
86.4
N.A.
38.9
88.7
N.A.
34.1
64.6
37
38.6
N.A.
24.4
25.3
N.A.
34.1
Protein Similarity:
100
54.9
55.1
88.3
N.A.
55.7
92.4
N.A.
49.4
76.7
54.6
55.2
N.A.
41.8
44.6
N.A.
50.4
P-Site Identity:
100
6.6
6.6
86.6
N.A.
6.6
93.3
N.A.
20
6.6
6.6
20
N.A.
40
6.6
N.A.
46.6
P-Site Similarity:
100
20
20
93.3
N.A.
20
100
N.A.
26.6
13.3
26.6
20
N.A.
60
20
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
24
8
8
0
0
0
8
0
0
0
24
0
% A
% Cys:
0
0
8
0
0
0
0
0
0
39
0
0
39
0
0
% C
% Asp:
0
0
16
0
24
0
0
0
0
0
16
0
0
8
0
% D
% Glu:
0
0
31
0
24
0
0
0
0
0
31
0
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
0
24
0
0
0
% F
% Gly:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
8
0
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
0
16
0
16
0
0
0
0
0
16
% I
% Lys:
16
8
0
8
0
0
31
8
0
0
0
16
0
8
16
% K
% Leu:
8
77
0
31
0
8
0
0
0
0
16
0
16
0
24
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
8
0
39
0
8
0
0
0
8
0
0
0
% N
% Pro:
8
0
0
0
31
0
0
8
0
0
8
8
16
8
0
% P
% Gln:
0
0
0
8
0
0
8
0
0
0
0
8
0
8
0
% Q
% Arg:
16
0
0
0
0
8
39
31
0
0
0
0
0
0
0
% R
% Ser:
8
16
0
0
0
8
8
8
8
0
31
31
24
31
47
% S
% Thr:
0
0
24
0
0
0
0
0
24
39
0
8
0
8
0
% T
% Val:
39
0
16
8
16
31
0
0
8
8
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
39
31
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _