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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CPSF2
All Species:
29.7
Human Site:
S516
Identified Species:
43.56
UniProt:
Q9P2I0
Number Species:
15
Phosphosite Substitution
Charge Score:
0.4
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P2I0
NP_059133.1
782
88487
S516
E
P
M
D
Q
D
L
S
D
V
P
T
K
C
I
Chimpanzee
Pan troglodytes
XP_001147204
731
82848
I501
D
G
D
S
I
K
K
I
I
N
Q
M
K
P
R
Rhesus Macaque
Macaca mulatta
XP_001092942
782
88454
S516
E
P
M
D
Q
D
L
S
D
V
P
T
K
C
I
Dog
Lupus familis
XP_537353
782
88470
S516
E
P
M
D
Q
D
L
S
D
V
P
T
K
C
I
Cat
Felis silvestris
Mouse
Mus musculus
O35218
782
88364
S516
E
P
M
D
Q
D
L
S
D
V
P
T
K
C
V
Rat
Rattus norvegicus
Q3MHC2
600
67822
E371
L
S
G
Q
R
K
L
E
M
E
G
R
Q
M
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507374
782
88381
S516
E
P
M
D
Q
D
L
S
D
V
P
T
K
C
I
Chicken
Gallus gallus
Q5ZIH0
600
68170
E371
L
S
G
Q
R
K
L
E
M
E
G
R
Q
I
L
Frog
Xenopus laevis
Q9W799
783
88968
S516
E
P
M
D
Q
D
L
S
D
V
P
T
K
C
V
Zebra Danio
Brachydanio rerio
NP_001002384
790
89603
S517
E
P
M
E
Q
D
L
S
D
V
P
T
K
C
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3D6
756
85400
E512
E
E
P
G
I
G
A
E
Q
Q
A
N
G
G
I
Honey Bee
Apis mellifera
XP_394940
737
83538
T508
A
H
H
P
E
I
P
T
D
I
P
T
K
C
I
Nematode Worm
Caenorhab. elegans
O17403
843
95598
E550
Y
N
P
N
D
H
V
E
E
M
P
T
K
C
V
Sea Urchin
Strong. purpuratus
XP_780045
776
88380
C518
K
K
I
D
K
D
Q
C
D
I
P
T
K
C
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LKF9
739
82121
D507
M
H
N
G
G
D
V
D
G
R
L
D
E
A
T
Baker's Yeast
Sacchar. cerevisiae
Q06224
779
87655
D525
Q
A
E
K
G
L
V
D
E
E
E
H
K
D
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.4
99.8
99.6
N.A.
97.9
23.6
N.A.
98.4
23.6
91.3
86
N.A.
56
59.5
42.4
61.1
Protein Similarity:
100
93.4
100
99.8
N.A.
99.6
39.7
N.A.
99.4
40
96.8
93.1
N.A.
72.1
76.5
63.9
77.2
P-Site Identity:
100
6.6
100
100
N.A.
93.3
6.6
N.A.
100
6.6
93.3
86.6
N.A.
13.3
40
26.6
53.3
P-Site Similarity:
100
13.3
100
100
N.A.
100
26.6
N.A.
100
26.6
100
93.3
N.A.
13.3
60
60
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.4
20
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
57.4
41.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
0
0
0
0
7
0
0
0
7
0
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
7
0
0
0
0
0
63
0
% C
% Asp:
7
0
7
44
7
57
0
13
57
0
0
7
0
7
0
% D
% Glu:
50
7
7
7
7
0
0
25
13
19
7
0
7
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
7
13
13
13
7
0
0
7
0
13
0
7
7
0
% G
% His:
0
13
7
0
0
7
0
0
0
0
0
7
0
0
0
% H
% Ile:
0
0
7
0
13
7
0
7
7
13
0
0
0
7
50
% I
% Lys:
7
7
0
7
7
19
7
0
0
0
0
0
75
0
0
% K
% Leu:
13
0
0
0
0
7
57
0
0
0
7
0
0
0
13
% L
% Met:
7
0
44
0
0
0
0
0
13
7
0
7
0
7
0
% M
% Asn:
0
7
7
7
0
0
0
0
0
7
0
7
0
0
0
% N
% Pro:
0
44
13
7
0
0
7
0
0
0
63
0
0
7
0
% P
% Gln:
7
0
0
13
44
0
7
0
7
7
7
0
13
0
0
% Q
% Arg:
0
0
0
0
13
0
0
0
0
7
0
13
0
0
7
% R
% Ser:
0
13
0
7
0
0
0
44
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
7
0
0
0
63
0
0
13
% T
% Val:
0
0
0
0
0
0
19
0
0
44
0
0
0
0
19
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _