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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CPSF2
All Species:
27.27
Human Site:
T505
Identified Species:
40
UniProt:
Q9P2I0
Number Species:
15
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P2I0
NP_059133.1
782
88487
T505
S
K
L
E
S
G
L
T
N
G
D
E
P
M
D
Chimpanzee
Pan troglodytes
XP_001147204
731
82848
E490
R
V
T
Y
I
D
Y
E
G
R
S
D
G
D
S
Rhesus Macaque
Macaca mulatta
XP_001092942
782
88454
T505
S
K
L
E
S
G
L
T
N
G
D
E
P
M
D
Dog
Lupus familis
XP_537353
782
88470
T505
S
K
L
E
S
G
L
T
N
G
D
E
P
M
D
Cat
Felis silvestris
Mouse
Mus musculus
O35218
782
88364
T505
S
K
L
E
S
G
L
T
N
G
E
E
P
M
D
Rat
Rattus norvegicus
Q3MHC2
600
67822
G360
Y
C
V
Q
G
T
V
G
H
K
I
L
S
G
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507374
782
88381
T505
S
K
L
E
S
G
L
T
N
G
D
E
P
M
D
Chicken
Gallus gallus
Q5ZIH0
600
68170
G360
Y
C
V
Q
G
T
V
G
H
K
I
L
S
G
Q
Frog
Xenopus laevis
Q9W799
783
88968
T505
T
K
L
E
S
G
L
T
N
G
D
E
P
M
D
Zebra Danio
Brachydanio rerio
NP_001002384
790
89603
T506
S
K
L
E
S
G
L
T
N
G
E
E
P
M
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3D6
756
85400
N501
M
E
E
Q
N
K
E
N
V
K
K
E
E
P
G
Honey Bee
Apis mellifera
XP_394940
737
83538
Q497
K
E
N
L
E
T
K
Q
E
D
T
A
H
H
P
Nematode Worm
Caenorhab. elegans
O17403
843
95598
E539
V
V
K
K
R
E
E
E
E
E
V
Y
N
P
N
Sea Urchin
Strong. purpuratus
XP_780045
776
88380
R507
V
K
V
G
S
G
Q
R
T
G
K
K
K
I
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LKF9
739
82121
D496
V
I
K
D
E
D
M
D
R
G
A
M
H
N
G
Baker's Yeast
Sacchar. cerevisiae
Q06224
779
87655
N514
I
K
E
E
N
E
D
N
L
D
S
Q
A
E
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.4
99.8
99.6
N.A.
97.9
23.6
N.A.
98.4
23.6
91.3
86
N.A.
56
59.5
42.4
61.1
Protein Similarity:
100
93.4
100
99.8
N.A.
99.6
39.7
N.A.
99.4
40
96.8
93.1
N.A.
72.1
76.5
63.9
77.2
P-Site Identity:
100
0
100
100
N.A.
93.3
0
N.A.
100
0
93.3
86.6
N.A.
6.6
0
0
33.3
P-Site Similarity:
100
6.6
100
100
N.A.
100
26.6
N.A.
100
26.6
100
100
N.A.
26.6
6.6
13.3
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.4
20
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
57.4
41.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
7
7
7
0
0
% A
% Cys:
0
13
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
7
0
13
7
7
0
13
32
7
0
7
44
% D
% Glu:
0
13
13
50
13
13
13
13
13
7
13
50
7
7
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
7
13
50
0
13
7
57
0
0
7
13
13
% G
% His:
0
0
0
0
0
0
0
0
13
0
0
0
13
7
0
% H
% Ile:
7
7
0
0
7
0
0
0
0
0
13
0
0
7
0
% I
% Lys:
7
57
13
7
0
7
7
0
0
19
13
7
7
0
7
% K
% Leu:
0
0
44
7
0
0
44
0
7
0
0
13
0
0
0
% L
% Met:
7
0
0
0
0
0
7
0
0
0
0
7
0
44
0
% M
% Asn:
0
0
7
0
13
0
0
13
44
0
0
0
7
7
7
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
44
13
7
% P
% Gln:
0
0
0
19
0
0
7
7
0
0
0
7
0
0
13
% Q
% Arg:
7
0
0
0
7
0
0
7
7
7
0
0
0
0
0
% R
% Ser:
38
0
0
0
50
0
0
0
0
0
13
0
13
0
7
% S
% Thr:
7
0
7
0
0
19
0
44
7
0
7
0
0
0
0
% T
% Val:
19
13
19
0
0
0
13
0
7
0
7
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
13
0
0
7
0
0
7
0
0
0
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _