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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CPSF2 All Species: 26.67
Human Site: T699 Identified Species: 39.11
UniProt: Q9P2I0 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P2I0 NP_059133.1 782 88487 T699 E E S E I I P T L E P L P P H
Chimpanzee Pan troglodytes XP_001147204 731 82848 F664 V P G H Q S V F M N E P R L S
Rhesus Macaque Macaca mulatta XP_001092942 782 88454 T699 E E S E I I P T L E P L P P H
Dog Lupus familis XP_537353 782 88470 T699 E E S E I I P T L E P L P P H
Cat Felis silvestris
Mouse Mus musculus O35218 782 88364 T699 E E T E I I P T L E P L P P H
Rat Rattus norvegicus Q3MHC2 600 67822 L534 A L R V Y S H L K S T L K D H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507374 782 88381 T699 E E S E I I P T L E P L P P H
Chicken Gallus gallus Q5ZIH0 600 68170 L534 V L R V Y N H L K G V L K D Y
Frog Xenopus laevis Q9W799 783 88968 T700 E E S E I I P T L E P L P S N
Zebra Danio Brachydanio rerio NP_001002384 790 89603 T707 E E S D V I P T L E P L P A H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V3D6 756 85400 N685 D D E I P I H N S V L I N E L
Honey Bee Apis mellifera XP_394940 737 83538 N671 G H Q T T F I N E L K L S D F
Nematode Worm Caenorhab. elegans O17403 843 95598 I759 G K I R G N L I L D P L P K R
Sea Urchin Strong. purpuratus XP_780045 776 88380 V693 D E D D I I P V L D A V Q T N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LKF9 739 82121 Q672 L K I A D F K Q F L S S K G V
Baker's Yeast Sacchar. cerevisiae Q06224 779 87655 Q702 D E V E R V K Q I S R L F K E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.4 99.8 99.6 N.A. 97.9 23.6 N.A. 98.4 23.6 91.3 86 N.A. 56 59.5 42.4 61.1
Protein Similarity: 100 93.4 100 99.8 N.A. 99.6 39.7 N.A. 99.4 40 96.8 93.1 N.A. 72.1 76.5 63.9 77.2
P-Site Identity: 100 0 100 100 N.A. 93.3 13.3 N.A. 100 6.6 86.6 80 N.A. 6.6 6.6 26.6 33.3
P-Site Similarity: 100 6.6 100 100 N.A. 100 13.3 N.A. 100 13.3 93.3 93.3 N.A. 26.6 6.6 40 66.6
Percent
Protein Identity: N.A. N.A. N.A. 37.4 20 N.A.
Protein Similarity: N.A. N.A. N.A. 57.4 41.8 N.A.
P-Site Identity: N.A. N.A. N.A. 0 20 N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 0 7 0 0 0 0 0 0 7 0 0 7 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 19 7 7 13 7 0 0 0 0 13 0 0 0 19 0 % D
% Glu: 44 57 7 44 0 0 0 0 7 44 7 0 0 7 7 % E
% Phe: 0 0 0 0 0 13 0 7 7 0 0 0 7 0 7 % F
% Gly: 13 0 7 0 7 0 0 0 0 7 0 0 0 7 0 % G
% His: 0 7 0 7 0 0 19 0 0 0 0 0 0 0 44 % H
% Ile: 0 0 13 7 44 57 7 7 7 0 0 7 0 0 0 % I
% Lys: 0 13 0 0 0 0 13 0 13 0 7 0 19 13 0 % K
% Leu: 7 13 0 0 0 0 7 13 57 13 7 75 0 7 7 % L
% Met: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 13 0 13 0 7 0 0 7 0 13 % N
% Pro: 0 7 0 0 7 0 50 0 0 0 50 7 50 32 0 % P
% Gln: 0 0 7 0 7 0 0 13 0 0 0 0 7 0 0 % Q
% Arg: 0 0 13 7 7 0 0 0 0 0 7 0 7 0 7 % R
% Ser: 0 0 38 0 0 13 0 0 7 13 7 7 7 7 7 % S
% Thr: 0 0 7 7 7 0 0 44 0 0 7 0 0 7 0 % T
% Val: 13 0 7 13 7 7 7 7 0 7 7 7 0 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 13 0 0 0 0 0 0 0 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _