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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CPSF2
All Species:
31.52
Human Site:
T753
Identified Species:
46.22
UniProt:
Q9P2I0
Number Species:
15
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P2I0
NP_059133.1
782
88487
T753
N
Q
V
A
V
R
R
T
E
T
G
R
I
G
L
Chimpanzee
Pan troglodytes
XP_001147204
731
82848
T702
N
Q
V
A
V
R
R
T
E
T
G
R
I
G
L
Rhesus Macaque
Macaca mulatta
XP_001092942
782
88454
T753
N
Q
V
A
V
R
R
T
E
T
G
R
I
G
L
Dog
Lupus familis
XP_537353
782
88470
T753
N
Q
V
A
V
R
R
T
E
T
G
R
I
G
L
Cat
Felis silvestris
Mouse
Mus musculus
O35218
782
88364
T753
N
Q
V
A
V
R
R
T
E
T
G
R
I
G
L
Rat
Rattus norvegicus
Q3MHC2
600
67822
L572
E
D
P
G
T
K
V
L
L
V
S
W
T
Y
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507374
782
88381
T753
N
L
V
A
V
R
R
T
E
T
G
R
I
G
L
Chicken
Gallus gallus
Q5ZIH0
600
68170
L572
E
D
Q
G
T
K
V
L
L
V
S
W
T
Y
Q
Frog
Xenopus laevis
Q9W799
783
88968
T754
N
M
V
A
V
R
R
T
E
T
G
R
I
G
L
Zebra Danio
Brachydanio rerio
NP_001002384
790
89603
T761
N
L
V
A
V
R
R
T
E
A
G
R
I
C
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3D6
756
85400
V727
G
T
L
A
L
R
R
V
D
A
G
K
V
A
M
Honey Bee
Apis mellifera
XP_394940
737
83538
E709
T
I
A
V
R
R
H
E
A
G
K
V
I
L
E
Nematode Worm
Caenorhab. elegans
O17403
843
95598
N814
G
N
C
S
I
R
R
N
D
T
G
V
F
Q
M
Sea Urchin
Strong. purpuratus
XP_780045
776
88380
N747
N
T
V
A
I
K
R
N
E
K
G
H
L
T
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LKF9
739
82121
S710
T
G
Q
K
G
G
A
S
G
P
Q
Q
I
L
I
Baker's Yeast
Sacchar. cerevisiae
Q06224
779
87655
D746
G
K
S
T
A
K
I
D
F
N
N
M
K
I
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.4
99.8
99.6
N.A.
97.9
23.6
N.A.
98.4
23.6
91.3
86
N.A.
56
59.5
42.4
61.1
Protein Similarity:
100
93.4
100
99.8
N.A.
99.6
39.7
N.A.
99.4
40
96.8
93.1
N.A.
72.1
76.5
63.9
77.2
P-Site Identity:
100
100
100
100
N.A.
100
0
N.A.
93.3
0
93.3
80
N.A.
26.6
13.3
26.6
46.6
P-Site Similarity:
100
100
100
100
N.A.
100
6.6
N.A.
93.3
6.6
93.3
80
N.A.
66.6
13.3
53.3
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.4
20
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
57.4
41.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
63
7
0
7
0
7
13
0
0
0
7
0
% A
% Cys:
0
0
7
0
0
0
0
0
0
0
0
0
0
7
0
% C
% Asp:
0
13
0
0
0
0
0
7
13
0
0
0
0
0
0
% D
% Glu:
13
0
0
0
0
0
0
7
57
0
0
0
0
0
7
% E
% Phe:
0
0
0
0
0
0
0
0
7
0
0
0
7
0
0
% F
% Gly:
19
7
0
13
7
7
0
0
7
7
69
0
0
44
0
% G
% His:
0
0
0
0
0
0
7
0
0
0
0
7
0
0
0
% H
% Ile:
0
7
0
0
13
0
7
0
0
0
0
0
63
7
7
% I
% Lys:
0
7
0
7
0
25
0
0
0
7
7
7
7
0
0
% K
% Leu:
0
13
7
0
7
0
0
13
13
0
0
0
7
13
63
% L
% Met:
0
7
0
0
0
0
0
0
0
0
0
7
0
0
13
% M
% Asn:
57
7
0
0
0
0
0
13
0
7
7
0
0
0
0
% N
% Pro:
0
0
7
0
0
0
0
0
0
7
0
0
0
0
0
% P
% Gln:
0
32
13
0
0
0
0
0
0
0
7
7
0
7
13
% Q
% Arg:
0
0
0
0
7
69
69
0
0
0
0
50
0
0
0
% R
% Ser:
0
0
7
7
0
0
0
7
0
0
13
0
0
0
0
% S
% Thr:
13
13
0
7
13
0
0
50
0
50
0
0
13
7
0
% T
% Val:
0
0
57
7
50
0
13
7
0
13
0
13
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
13
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
13
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _