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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CPSF2
All Species:
30.61
Human Site:
Y540
Identified Species:
44.89
UniProt:
Q9P2I0
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P2I0
NP_059133.1
782
88487
Y540
A
R
V
T
Y
I
D
Y
E
G
R
S
D
G
D
Chimpanzee
Pan troglodytes
XP_001147204
731
82848
E525
E
A
S
Q
D
L
A
E
C
C
R
A
F
G
G
Rhesus Macaque
Macaca mulatta
XP_001092942
782
88454
Y540
A
R
V
T
Y
I
D
Y
E
G
R
S
D
G
D
Dog
Lupus familis
XP_537353
782
88470
Y540
A
R
V
T
Y
I
D
Y
E
G
R
S
D
G
D
Cat
Felis silvestris
Mouse
Mus musculus
O35218
782
88364
Y540
A
R
V
T
Y
I
D
Y
E
G
R
S
D
G
D
Rat
Rattus norvegicus
Q3MHC2
600
67822
A395
S
F
S
A
H
A
D
A
K
G
I
M
Q
L
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507374
782
88381
Y540
A
R
V
T
Y
I
D
Y
E
G
R
S
D
G
D
Chicken
Gallus gallus
Q5ZIH0
600
68170
A395
S
F
S
A
H
A
D
A
K
G
I
M
Q
L
I
Frog
Xenopus laevis
Q9W799
783
88968
Y540
A
R
V
T
Y
I
D
Y
E
G
R
S
D
G
D
Zebra Danio
Brachydanio rerio
NP_001002384
790
89603
Y541
A
R
V
M
Y
I
D
Y
E
G
R
S
D
G
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3D6
756
85400
Q536
K
P
T
K
L
I
S
Q
R
K
T
I
E
V
N
Honey Bee
Apis mellifera
XP_394940
737
83538
F532
A
S
V
T
Y
I
D
F
E
G
R
S
D
G
E
Nematode Worm
Caenorhab. elegans
O17403
843
95598
Y574
C
R
I
E
F
I
E
Y
E
G
I
S
D
G
E
Sea Urchin
Strong. purpuratus
XP_780045
776
88380
F542
C
S
I
T
F
I
D
F
E
G
R
S
D
G
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LKF9
739
82121
L531
S
K
V
M
S
N
E
L
I
V
T
V
S
C
S
Baker's Yeast
Sacchar. cerevisiae
Q06224
779
87655
F549
D
K
N
F
E
L
D
F
L
S
L
S
D
L
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.4
99.8
99.6
N.A.
97.9
23.6
N.A.
98.4
23.6
91.3
86
N.A.
56
59.5
42.4
61.1
Protein Similarity:
100
93.4
100
99.8
N.A.
99.6
39.7
N.A.
99.4
40
96.8
93.1
N.A.
72.1
76.5
63.9
77.2
P-Site Identity:
100
13.3
100
100
N.A.
100
13.3
N.A.
100
13.3
100
93.3
N.A.
6.6
80
53.3
60
P-Site Similarity:
100
26.6
100
100
N.A.
100
33.3
N.A.
100
33.3
100
93.3
N.A.
20
93.3
80
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.4
20
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
57.4
41.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
50
7
0
13
0
13
7
13
0
0
0
7
0
0
0
% A
% Cys:
13
0
0
0
0
0
0
0
7
7
0
0
0
7
0
% C
% Asp:
7
0
0
0
7
0
75
0
0
0
0
0
69
0
44
% D
% Glu:
7
0
0
7
7
0
13
7
63
0
0
0
7
0
19
% E
% Phe:
0
13
0
7
13
0
0
19
0
0
0
0
7
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
75
0
0
0
69
7
% G
% His:
0
0
0
0
13
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
13
0
0
69
0
0
7
0
19
7
0
0
7
% I
% Lys:
7
13
0
7
0
0
0
0
13
7
0
0
0
0
0
% K
% Leu:
0
0
0
0
7
13
0
7
7
0
7
0
0
19
0
% L
% Met:
0
0
0
13
0
0
0
0
0
0
0
13
0
0
0
% M
% Asn:
0
0
7
0
0
7
0
0
0
0
0
0
0
0
7
% N
% Pro:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
7
0
0
0
7
0
0
0
0
13
0
0
% Q
% Arg:
0
50
0
0
0
0
0
0
7
0
63
0
0
0
7
% R
% Ser:
19
13
19
0
7
0
7
0
0
7
0
69
7
0
7
% S
% Thr:
0
0
7
50
0
0
0
0
0
0
13
0
0
0
0
% T
% Val:
0
0
57
0
0
0
0
0
0
7
0
7
0
7
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
50
0
0
50
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _