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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KLHL9
All Species:
13.64
Human Site:
S605
Identified Species:
30
UniProt:
Q9P2J3
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P2J3
NP_061335.1
617
69429
S605
E
E
N
P
G
S
P
S
R
E
S
P
L
S
A
Chimpanzee
Pan troglodytes
XP_520510
714
79585
S702
E
E
N
P
G
S
P
S
R
E
S
P
L
S
A
Rhesus Macaque
Macaca mulatta
XP_001099179
618
69588
P607
F
P
P
E
E
T
T
P
S
P
S
R
E
S
P
Dog
Lupus familis
XP_538682
952
103252
S940
E
E
N
P
G
S
P
S
R
E
S
P
L
S
A
Cat
Felis silvestris
Mouse
Mus musculus
Q6ZPT1
617
69381
S605
E
E
N
P
G
S
P
S
R
E
S
P
L
S
A
Rat
Rattus norvegicus
Q66HD2
613
69917
K601
N
P
R
L
E
E
K
K
K
K
N
K
D
K
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515201
608
68274
M593
Y
S
W
N
N
R
C
M
V
E
I
V
Q
K
Y
Chicken
Gallus gallus
Q5ZLD3
629
70952
G618
F
P
P
E
D
N
T
G
S
P
S
R
E
S
P
Frog
Xenopus laevis
NP_001086711
635
71326
C624
F
P
P
E
D
N
S
C
S
P
S
R
E
S
P
Zebra Danio
Brachydanio rerio
Q5RGB8
605
68516
C593
E
S
F
A
G
I
A
C
T
P
I
I
L
P
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUU5
623
68905
N610
M
R
A
P
Q
T
E
N
Y
M
W
C
E
N
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80.9
90.6
64.5
N.A.
98.6
36.1
N.A.
81.3
93.3
90.2
40.3
N.A.
31.6
N.A.
N.A.
N.A.
Protein Similarity:
100
82.7
94.9
64.7
N.A.
99.8
59.3
N.A.
86.7
95.7
94
59.9
N.A.
51.6
N.A.
N.A.
N.A.
P-Site Identity:
100
100
13.3
100
N.A.
100
0
N.A.
6.6
13.3
13.3
20
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
20
100
N.A.
100
20
N.A.
6.6
20
20
20
N.A.
33.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
10
0
0
10
0
0
0
0
0
0
0
37
% A
% Cys:
0
0
0
0
0
0
10
19
0
0
0
10
0
0
0
% C
% Asp:
0
0
0
0
19
0
0
0
0
0
0
0
10
0
0
% D
% Glu:
46
37
0
28
19
10
10
0
0
46
0
0
37
0
0
% E
% Phe:
28
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
46
0
0
10
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
10
0
0
0
0
19
10
0
0
0
% I
% Lys:
0
0
0
0
0
0
10
10
10
10
0
10
0
19
0
% K
% Leu:
0
0
0
10
0
0
0
0
0
0
0
0
46
0
0
% L
% Met:
10
0
0
0
0
0
0
10
0
10
0
0
0
0
0
% M
% Asn:
10
0
37
10
10
19
0
10
0
0
10
0
0
10
0
% N
% Pro:
0
37
28
46
0
0
37
10
0
37
0
37
0
10
28
% P
% Gln:
0
0
0
0
10
0
0
0
0
0
0
0
10
0
10
% Q
% Arg:
0
10
10
0
0
10
0
0
37
0
0
28
0
0
10
% R
% Ser:
0
19
0
0
0
37
10
37
28
0
64
0
0
64
10
% S
% Thr:
0
0
0
0
0
19
19
0
10
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
10
0
0
10
0
0
0
% V
% Trp:
0
0
10
0
0
0
0
0
0
0
10
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
0
10
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _