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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LARS All Species: 29.09
Human Site: S1042 Identified Species: 53.33
UniProt: Q9P2J5 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P2J5 NP_064502.9 1176 134466 S1042 H I E V K F A S E A E D K I R
Chimpanzee Pan troglodytes XP_001157096 1176 134469 S1042 H I E V K F A S E A E D K I R
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_535229 1176 134216 S1042 H I E V K F A S E A E D K V R
Cat Felis silvestris
Mouse Mus musculus Q8BMJ2 1178 134174 S1044 H I E V K F A S E A E D K V R
Rat Rattus norvegicus NP_001009637 1178 134260 S1044 H I D V K F A S E A E D K V R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_414663 1177 134257 S1043 H I E V K F A S E A E D K I K
Frog Xenopus laevis NP_001087393 1178 134087 S1044 Q I D L K F A S D A D D K V K
Zebra Danio Brachydanio rerio XP_698279 747 84899 S635 K P F C V F R S E P G V I I S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_787968 1182 134854 D1047 V L E I K Y T D D P S A P E K
Honey Bee Apis mellifera XP_395743 1181 136743 N1043 N I V I K Y T N E A P E K T R
Nematode Worm Caenorhab. elegans Q09996 1186 134501 D1046 R V T I R H T D E E G I D A N
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P26637 1090 124123 D977 L F S E Q T L D D N K K V R E
Red Bread Mold Neurospora crassa P10857 1123 126381 T1007 S E V W D A A T G T Q K I D D
Conservation
Percent
Protein Identity: 100 99.5 N.A. 94.9 N.A. 90 89.9 N.A. N.A. 87 82.5 50.5 N.A. 59.3 60.9 56.6 N.A.
Protein Similarity: 100 99.9 N.A. 97.5 N.A. 96.1 96 N.A. N.A. 93.5 92.6 57.4 N.A. 75.3 78.2 71.4 N.A.
P-Site Identity: 100 100 N.A. 93.3 N.A. 93.3 86.6 N.A. N.A. 93.3 53.3 26.6 N.A. 13.3 40 6.6 N.A.
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. N.A. 100 93.3 26.6 N.A. 46.6 73.3 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 43.7 43.8
Protein Similarity: N.A. N.A. N.A. N.A. 61.1 61.6
P-Site Identity: N.A. N.A. N.A. N.A. 0 6.6
P-Site Similarity: N.A. N.A. N.A. N.A. 20 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 8 62 0 0 62 0 8 0 8 0 % A
% Cys: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 16 0 8 0 0 24 24 0 8 54 8 8 8 % D
% Glu: 0 8 47 8 0 0 0 0 70 8 47 8 0 8 8 % E
% Phe: 0 8 8 0 0 62 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 8 0 16 0 0 0 0 % G
% His: 47 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 62 0 24 0 0 0 0 0 0 0 8 16 31 0 % I
% Lys: 8 0 0 0 70 0 0 0 0 0 8 16 62 0 24 % K
% Leu: 8 8 0 8 0 0 8 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 0 0 0 0 0 0 8 0 8 0 0 0 0 8 % N
% Pro: 0 8 0 0 0 0 0 0 0 16 8 0 8 0 0 % P
% Gln: 8 0 0 0 8 0 0 0 0 0 8 0 0 0 0 % Q
% Arg: 8 0 0 0 8 0 8 0 0 0 0 0 0 8 47 % R
% Ser: 8 0 8 0 0 0 0 62 0 0 8 0 0 0 8 % S
% Thr: 0 0 8 0 0 8 24 8 0 8 0 0 0 8 0 % T
% Val: 8 8 16 47 8 0 0 0 0 0 0 8 8 31 0 % V
% Trp: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 16 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _