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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LARS All Species: 42.12
Human Site: T390 Identified Species: 77.22
UniProt: Q9P2J5 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P2J5 NP_064502.9 1176 134466 T390 D K G T G V V T S V P S D S P
Chimpanzee Pan troglodytes XP_001157096 1176 134469 T390 D K G T G V V T S V P S D S P
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_535229 1176 134216 T390 D K G T G V V T S V P S D S P
Cat Felis silvestris
Mouse Mus musculus Q8BMJ2 1178 134174 T392 D K G T G V V T S V P S D S P
Rat Rattus norvegicus NP_001009637 1178 134260 T392 D K G T G V V T S V P S D S P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_414663 1177 134257 T391 D K G T G V V T S V P S D S P
Frog Xenopus laevis NP_001087393 1178 134087 T392 D K G T G V V T S V P S D A P
Zebra Danio Brachydanio rerio XP_698279 747 84899 L50 G F Y E G I M L V E G F K G Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_787968 1182 134854 T390 D K G T G V V T S V P S D S P
Honey Bee Apis mellifera XP_395743 1181 136743 T388 D K G T G I V T S V P S D S P
Nematode Worm Caenorhab. elegans Q09996 1186 134501 T391 D K G T G V V T S V P S D S P
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P26637 1090 124123 L392 P Q S V Y P E L R I L P M E T
Red Bread Mold Neurospora crassa P10857 1123 126381 T419 V Y V L P M D T V L A T K G T
Conservation
Percent
Protein Identity: 100 99.5 N.A. 94.9 N.A. 90 89.9 N.A. N.A. 87 82.5 50.5 N.A. 59.3 60.9 56.6 N.A.
Protein Similarity: 100 99.9 N.A. 97.5 N.A. 96.1 96 N.A. N.A. 93.5 92.6 57.4 N.A. 75.3 78.2 71.4 N.A.
P-Site Identity: 100 100 N.A. 100 N.A. 100 100 N.A. N.A. 100 93.3 6.6 N.A. 100 93.3 100 N.A.
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. N.A. 100 100 20 N.A. 100 100 100 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 43.7 43.8
Protein Similarity: N.A. N.A. N.A. N.A. 61.1 61.6
P-Site Identity: N.A. N.A. N.A. N.A. 0 6.6
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 8 0 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 77 0 0 0 0 0 8 0 0 0 0 0 77 0 0 % D
% Glu: 0 0 0 8 0 0 8 0 0 8 0 0 0 8 0 % E
% Phe: 0 8 0 0 0 0 0 0 0 0 0 8 0 0 0 % F
% Gly: 8 0 77 0 85 0 0 0 0 0 8 0 0 16 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 16 0 0 0 8 0 0 0 0 0 % I
% Lys: 0 77 0 0 0 0 0 0 0 0 0 0 16 0 0 % K
% Leu: 0 0 0 8 0 0 0 16 0 8 8 0 0 0 0 % L
% Met: 0 0 0 0 0 8 8 0 0 0 0 0 8 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 8 0 0 0 8 8 0 0 0 0 77 8 0 0 77 % P
% Gln: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 8 % Q
% Arg: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % R
% Ser: 0 0 8 0 0 0 0 0 77 0 0 77 0 70 0 % S
% Thr: 0 0 0 77 0 0 0 85 0 0 0 8 0 0 16 % T
% Val: 8 0 8 8 0 70 77 0 16 77 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 8 0 8 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _