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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LARS All Species: 30.91
Human Site: Y985 Identified Species: 56.67
UniProt: Q9P2J5 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P2J5 NP_064502.9 1176 134466 Y985 S M P E L K K Y M K K V M P F
Chimpanzee Pan troglodytes XP_001157096 1176 134469 Y985 S M P E L K K Y M K K V M P F
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_535229 1176 134216 Y985 N L P E L K K Y M K K V M P F
Cat Felis silvestris
Mouse Mus musculus Q8BMJ2 1178 134174 Y987 S L P E L K K Y M K K V M P F
Rat Rattus norvegicus NP_001009637 1178 134260 Y987 S L P E L K K Y M K K V M P F
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_414663 1177 134257 Y986 A L P E L K K Y M K K V M P F
Frog Xenopus laevis NP_001087393 1178 134087 Y987 A L P E L K K Y M K R V M P F
Zebra Danio Brachydanio rerio XP_698279 747 84899 E604 V Y L T N S L E L D Q I D V V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_787968 1182 134854 F989 Q K A E L K K F M K R V M P F
Honey Bee Apis mellifera XP_395743 1181 136743 Y986 K H Q E L K K Y M K R L M P F
Nematode Worm Caenorhab. elegans Q09996 1186 134501 F989 K E E S L K K F A K K A M P F
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P26637 1090 124123 V946 E I D A S K P V K L T L L I S
Red Bread Mold Neurospora crassa P10857 1123 126381 K976 Q S D F D P K K P K K L T I F
Conservation
Percent
Protein Identity: 100 99.5 N.A. 94.9 N.A. 90 89.9 N.A. N.A. 87 82.5 50.5 N.A. 59.3 60.9 56.6 N.A.
Protein Similarity: 100 99.9 N.A. 97.5 N.A. 96.1 96 N.A. N.A. 93.5 92.6 57.4 N.A. 75.3 78.2 71.4 N.A.
P-Site Identity: 100 100 N.A. 86.6 N.A. 93.3 93.3 N.A. N.A. 86.6 80 0 N.A. 66.6 66.6 53.3 N.A.
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. N.A. 100 100 20 N.A. 80 80 60 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 43.7 43.8
Protein Similarity: N.A. N.A. N.A. N.A. 61.1 61.6
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 26.6
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 16 0 8 8 0 0 0 0 8 0 0 8 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 16 0 8 0 0 0 0 8 0 0 8 0 0 % D
% Glu: 8 8 8 70 0 0 0 8 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 8 0 0 0 16 0 0 0 0 0 0 85 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 0 0 0 0 0 0 0 0 0 8 0 16 0 % I
% Lys: 16 8 0 0 0 85 85 8 8 85 62 0 0 0 0 % K
% Leu: 0 39 8 0 77 0 8 0 8 8 0 24 8 0 0 % L
% Met: 0 16 0 0 0 0 0 0 70 0 0 0 77 0 0 % M
% Asn: 8 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 54 0 0 8 8 0 8 0 0 0 0 77 0 % P
% Gln: 16 0 8 0 0 0 0 0 0 0 8 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 24 0 0 0 0 % R
% Ser: 31 8 0 8 8 8 0 0 0 0 0 0 0 0 8 % S
% Thr: 0 0 0 8 0 0 0 0 0 0 8 0 8 0 0 % T
% Val: 8 0 0 0 0 0 0 8 0 0 0 62 0 8 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 0 0 0 62 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _