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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KLHDC5 All Species: 10.91
Human Site: S277 Identified Species: 30
UniProt: Q9P2K6 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P2K6 NP_065833.1 505 56868 S277 A A H S Y N P S T N E W L Q V
Chimpanzee Pan troglodytes XP_524579 777 84267 A522 Q D V W R P L A R L P P E A V
Rhesus Macaque Macaca mulatta XP_001100422 533 59810 S305 A A H S Y N P S T N E W L Q V
Dog Lupus familis XP_534854 479 54099 S251 A A H S Y N P S T N E W L Q V
Cat Felis silvestris
Mouse Mus musculus Q8BFQ9 493 55580 I265 A A H S Y N P I T N E W L Q V
Rat Rattus norvegicus Q66HD2 613 69917 R371 L L Y R Y D P R R K Q W I K V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515274 806 86681 L462 A P Q V H L D L G N C L N V L
Chicken Gallus gallus Q5ZLD3 629 70952 R391 T V F R F D P R Y N K W M Q V
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q5RGB8 605 68516 T327 V Y F L P D I T V R Q F K E L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 20.9 75.9 93 N.A. 91.2 20.5 N.A. 20.8 22.8 N.A. 21.4 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 34.4 80.3 94 N.A. 94.4 40.7 N.A. 35.3 40.3 N.A. 40 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 6.6 100 100 N.A. 93.3 26.6 N.A. 13.3 33.3 N.A. 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 13.3 100 100 N.A. 93.3 60 N.A. 26.6 60 N.A. 40 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 56 45 0 0 0 0 0 12 0 0 0 0 0 12 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 12 0 0 0 0 % C
% Asp: 0 12 0 0 0 34 12 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 45 0 12 12 0 % E
% Phe: 0 0 23 0 12 0 0 0 0 0 0 12 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 12 0 0 0 0 0 0 % G
% His: 0 0 45 0 12 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 12 12 0 0 0 0 12 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 12 12 0 12 12 0 % K
% Leu: 12 12 0 12 0 12 12 12 0 12 0 12 45 0 23 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 12 0 0 % M
% Asn: 0 0 0 0 0 45 0 0 0 67 0 0 12 0 0 % N
% Pro: 0 12 0 0 12 12 67 0 0 0 12 12 0 0 0 % P
% Gln: 12 0 12 0 0 0 0 0 0 0 23 0 0 56 0 % Q
% Arg: 0 0 0 23 12 0 0 23 23 12 0 0 0 0 0 % R
% Ser: 0 0 0 45 0 0 0 34 0 0 0 0 0 0 0 % S
% Thr: 12 0 0 0 0 0 0 12 45 0 0 0 0 0 0 % T
% Val: 12 12 12 12 0 0 0 0 12 0 0 0 0 12 78 % V
% Trp: 0 0 0 12 0 0 0 0 0 0 0 67 0 0 0 % W
% Tyr: 0 12 12 0 56 0 0 0 12 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _