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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KLHDC5
All Species:
14.55
Human Site:
S461
Identified Species:
40
UniProt:
Q9P2K6
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P2K6
NP_065833.1
505
56868
S461
M
S
R
D
V
T
L
S
T
S
L
E
H
R
V
Chimpanzee
Pan troglodytes
XP_524579
777
84267
C735
V
G
R
R
S
T
L
C
F
L
A
D
S
V
S
Rhesus Macaque
Macaca mulatta
XP_001100422
533
59810
S489
M
S
R
D
V
T
L
S
T
S
L
E
H
R
V
Dog
Lupus familis
XP_534854
479
54099
S435
M
S
R
D
V
T
L
S
T
S
L
E
H
R
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8BFQ9
493
55580
S449
M
S
R
D
V
T
L
S
T
S
L
E
H
R
V
Rat
Rattus norvegicus
Q66HD2
613
69917
R561
W
E
S
T
A
F
S
R
A
V
Q
V
Y
D
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515274
806
86681
Y674
V
T
G
G
T
L
R
Y
L
L
L
R
S
T
G
Chicken
Gallus gallus
Q5ZLD3
629
70952
I579
N
N
R
C
M
V
E
I
V
Q
K
Y
D
P
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5RGB8
605
68516
E520
C
F
D
V
L
A
V
E
Y
Y
I
P
E
T
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
20.9
75.9
93
N.A.
91.2
20.5
N.A.
20.8
22.8
N.A.
21.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
34.4
80.3
94
N.A.
94.4
40.7
N.A.
35.3
40.3
N.A.
40
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
20
100
100
N.A.
100
0
N.A.
6.6
6.6
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
33.3
100
100
N.A.
100
6.6
N.A.
20
20
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
12
12
0
0
12
0
12
0
0
0
0
% A
% Cys:
12
0
0
12
0
0
0
12
0
0
0
0
0
0
0
% C
% Asp:
0
0
12
45
0
0
0
0
0
0
0
12
12
12
12
% D
% Glu:
0
12
0
0
0
0
12
12
0
0
0
45
12
0
12
% E
% Phe:
0
12
0
0
0
12
0
0
12
0
0
0
0
0
0
% F
% Gly:
0
12
12
12
0
0
0
0
0
0
0
0
0
0
12
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
45
0
0
% H
% Ile:
0
0
0
0
0
0
0
12
0
0
12
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% K
% Leu:
0
0
0
0
12
12
56
0
12
23
56
0
0
0
0
% L
% Met:
45
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
12
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
12
0
12
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
12
12
0
0
0
0
% Q
% Arg:
0
0
67
12
0
0
12
12
0
0
0
12
0
45
12
% R
% Ser:
0
45
12
0
12
0
12
45
0
45
0
0
23
0
12
% S
% Thr:
0
12
0
12
12
56
0
0
45
0
0
0
0
23
0
% T
% Val:
23
0
0
12
45
12
12
0
12
12
0
12
0
12
45
% V
% Trp:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
12
12
12
0
12
12
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _