KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR35
All Species:
31.52
Human Site:
S489
Identified Species:
63.03
UniProt:
Q9P2L0
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P2L0
NP_001006658.1
1181
133547
S489
V
D
D
T
P
S
G
S
M
D
G
V
L
D
Y
Chimpanzee
Pan troglodytes
XP_515315
1273
143538
S581
V
D
D
T
P
S
G
S
M
D
G
A
L
D
Y
Rhesus Macaque
Macaca mulatta
XP_001107482
1296
146192
S604
V
D
D
T
P
S
G
S
M
D
G
V
L
D
Y
Dog
Lupus familis
XP_532884
1356
153148
S489
I
D
D
T
P
S
G
S
V
D
G
V
L
D
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q8BND3
1181
133947
S489
V
D
D
V
P
S
G
S
V
D
G
V
F
D
Y
Rat
Rattus norvegicus
NP_001092810
1170
132761
S478
V
D
D
V
P
S
G
S
V
D
G
V
F
D
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511461
679
76765
V54
L
E
G
H
S
G
S
V
Q
V
V
T
W
N
E
Chicken
Gallus gallus
XP_419970
1197
135555
S508
I
D
D
T
P
S
G
S
G
D
G
H
L
D
Y
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001139061
1203
136070
T509
I
D
D
S
P
S
G
T
S
D
G
T
L
N
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_647653
1205
135183
T496
K
R
F
H
I
D
D
T
P
T
G
V
E
M
A
Honey Bee
Apis mellifera
XP_394812
1185
134241
S494
K
D
R
S
F
E
A
S
I
N
T
K
A
T
M
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783217
1209
136043
A506
V
D
D
T
P
S
G
A
G
D
G
V
L
D
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.3
89.8
82
N.A.
92.2
91.7
N.A.
51.1
84.4
N.A.
78
N.A.
47.2
51.9
N.A.
66.3
Protein Similarity:
100
92.6
90.6
84.7
N.A.
96.7
96
N.A.
54.4
92.2
N.A.
88.4
N.A.
64.9
70.6
N.A.
80.5
P-Site Identity:
100
93.3
100
86.6
N.A.
80
80
N.A.
0
80
N.A.
53.3
N.A.
13.3
13.3
N.A.
80
P-Site Similarity:
100
93.3
100
100
N.A.
86.6
86.6
N.A.
20
86.6
N.A.
86.6
N.A.
20
33.3
N.A.
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
9
9
0
0
0
9
9
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
84
75
0
0
9
9
0
0
75
0
0
0
67
0
% D
% Glu:
0
9
0
0
0
9
0
0
0
0
0
0
9
0
9
% E
% Phe:
0
0
9
0
9
0
0
0
0
0
0
0
17
0
17
% F
% Gly:
0
0
9
0
0
9
75
0
17
0
84
0
0
0
0
% G
% His:
0
0
0
17
0
0
0
0
0
0
0
9
0
0
0
% H
% Ile:
25
0
0
0
9
0
0
0
9
0
0
0
0
0
0
% I
% Lys:
17
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% K
% Leu:
9
0
0
0
0
0
0
0
0
0
0
0
59
0
0
% L
% Met:
0
0
0
0
0
0
0
0
25
0
0
0
0
9
9
% M
% Asn:
0
0
0
0
0
0
0
0
0
9
0
0
0
17
0
% N
% Pro:
0
0
0
0
75
0
0
0
9
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% Q
% Arg:
0
9
9
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
17
9
75
9
67
9
0
0
0
0
0
0
% S
% Thr:
0
0
0
50
0
0
0
17
0
9
9
17
0
9
0
% T
% Val:
50
0
0
17
0
0
0
9
25
9
9
59
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
59
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _