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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBC1D14
All Species:
21.82
Human Site:
S441
Identified Species:
48
UniProt:
Q9P2M4
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P2M4
NP_001106832.1
693
78137
S441
K
E
R
W
R
S
L
S
T
G
G
S
E
V
E
Chimpanzee
Pan troglodytes
XP_526514
816
90725
S564
K
E
R
W
R
S
L
S
T
G
G
S
E
V
E
Rhesus Macaque
Macaca mulatta
XP_001118829
841
93630
S589
K
E
R
W
R
S
L
S
T
G
G
S
E
V
E
Dog
Lupus familis
XP_545899
718
80648
S466
K
E
R
W
R
S
F
S
A
G
G
S
E
A
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8CGA2
694
78297
S442
K
E
R
W
R
S
L
S
T
G
G
S
E
V
E
Rat
Rattus norvegicus
Q5CD77
694
78190
S442
K
E
R
W
R
S
L
S
T
G
G
S
E
V
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZJ17
816
92547
C555
V
W
Q
L
L
A
G
C
H
D
N
E
A
M
L
Frog
Xenopus laevis
NP_001121224
596
67729
K370
E
A
S
L
E
L
I
K
L
D
I
S
R
T
F
Zebra Danio
Brachydanio rerio
XP_683181
711
79655
P462
K
W
N
A
F
V
A
P
T
A
A
V
E
T
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395767
620
69571
C390
T
T
H
L
Y
N
I
C
L
E
R
A
I
S
S
Nematode Worm
Caenorhab. elegans
NP_508458
614
70009
L384
Y
D
H
L
L
K
L
L
S
A
Y
A
I
L
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.4
81.3
88.7
N.A.
90.6
90.6
N.A.
N.A.
20.7
53.2
61
N.A.
N.A.
34.6
34.2
N.A.
Protein Similarity:
100
84.8
82
91.7
N.A.
95.5
95.6
N.A.
N.A.
36.7
66.6
73.1
N.A.
N.A.
51.3
51.5
N.A.
P-Site Identity:
100
100
100
80
N.A.
100
100
N.A.
N.A.
0
6.6
26.6
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
100
100
100
80
N.A.
100
100
N.A.
N.A.
20
20
26.6
N.A.
N.A.
20
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
10
0
10
10
0
10
19
10
19
10
10
0
% A
% Cys:
0
0
0
0
0
0
0
19
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
0
0
0
19
0
0
0
0
0
% D
% Glu:
10
55
0
0
10
0
0
0
0
10
0
10
64
0
64
% E
% Phe:
0
0
0
0
10
0
10
0
0
0
0
0
0
0
10
% F
% Gly:
0
0
0
0
0
0
10
0
0
55
55
0
0
0
0
% G
% His:
0
0
19
0
0
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
19
0
0
0
10
0
19
0
0
% I
% Lys:
64
0
0
0
0
10
0
10
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
37
19
10
55
10
19
0
0
0
0
10
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
0
0
10
0
0
10
0
0
0
0
10
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% P
% Gln:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
55
0
55
0
0
0
0
0
10
0
10
0
10
% R
% Ser:
0
0
10
0
0
55
0
55
10
0
0
64
0
10
10
% S
% Thr:
10
10
0
0
0
0
0
0
55
0
0
0
0
19
0
% T
% Val:
10
0
0
0
0
10
0
0
0
0
0
10
0
46
0
% V
% Trp:
0
19
0
55
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
10
0
0
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _