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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADAMTS9
All Species:
9.09
Human Site:
Y574
Identified Species:
18.18
UniProt:
Q9P2N4
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P2N4
NP_891550.1
1935
216491
Y574
E
P
G
K
H
C
K
Y
G
F
C
V
P
K
E
Chimpanzee
Pan troglodytes
XP_528704
1935
216502
Y574
E
P
G
K
H
C
K
Y
G
F
C
V
P
K
E
Rhesus Macaque
Macaca mulatta
XP_001091856
1935
216539
Y574
E
P
G
K
H
C
K
Y
G
F
C
V
P
K
E
Dog
Lupus familis
XP_848393
1930
215924
F568
E
P
G
K
H
C
K
F
G
F
C
V
P
K
E
Cat
Felis silvestris
Mouse
Mus musculus
P59511
1906
212023
R539
G
P
G
M
H
C
H
R
G
L
C
V
T
R
D
Rat
Rattus norvegicus
Q9WUQ1
967
105687
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505519
1995
223408
G576
K
L
F
C
R
V
A
G
T
T
Y
Y
Y
Q
L
Chicken
Gallus gallus
XP_414417
1928
215452
F566
E
P
G
K
H
C
R
F
G
M
C
V
P
K
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002663807
2516
282446
H539
G
L
C
I
H
K
E
H
E
Y
V
P
V
E
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395557
1763
199932
L476
E
R
T
D
P
R
R
L
P
G
E
D
Y
S
V
Nematode Worm
Caenorhab. elegans
Q19791
2150
242563
G574
R
S
M
F
C
H
H
G
A
C
V
R
L
A
P
Sea Urchin
Strong. purpuratus
XP_791211
1693
190452
C406
H
W
C
S
H
G
E
C
R
E
K
E
Q
H
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
99.1
92.5
N.A.
54.2
24.1
N.A.
50.3
76.4
N.A.
40.7
N.A.
N.A.
32.9
33.2
39.2
Protein Similarity:
100
99.8
99.4
96.1
N.A.
69.4
32.2
N.A.
64.4
86.5
N.A.
51.9
N.A.
N.A.
47.9
48.9
54.5
P-Site Identity:
100
100
100
93.3
N.A.
46.6
0
N.A.
0
80
N.A.
6.6
N.A.
N.A.
6.6
0
6.6
P-Site Similarity:
100
100
100
100
N.A.
60
0
N.A.
13.3
93.3
N.A.
33.3
N.A.
N.A.
13.3
0
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
9
0
9
0
0
0
0
9
0
% A
% Cys:
0
0
17
9
9
50
0
9
0
9
50
0
0
0
0
% C
% Asp:
0
0
0
9
0
0
0
0
0
0
0
9
0
0
9
% D
% Glu:
50
0
0
0
0
0
17
0
9
9
9
9
0
9
42
% E
% Phe:
0
0
9
9
0
0
0
17
0
34
0
0
0
0
0
% F
% Gly:
17
0
50
0
0
9
0
17
50
9
0
0
0
0
9
% G
% His:
9
0
0
0
67
9
17
9
0
0
0
0
0
9
0
% H
% Ile:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
9
0
0
42
0
9
34
0
0
0
9
0
0
42
0
% K
% Leu:
0
17
0
0
0
0
0
9
0
9
0
0
9
0
9
% L
% Met:
0
0
9
9
0
0
0
0
0
9
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
50
0
0
9
0
0
0
9
0
0
9
42
0
9
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
9
9
0
% Q
% Arg:
9
9
0
0
9
9
17
9
9
0
0
9
0
9
0
% R
% Ser:
0
9
0
9
0
0
0
0
0
0
0
0
0
9
0
% S
% Thr:
0
0
9
0
0
0
0
0
9
9
0
0
9
0
9
% T
% Val:
0
0
0
0
0
9
0
0
0
0
17
50
9
0
9
% V
% Trp:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
25
0
9
9
9
17
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _