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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HECW2
All Species:
15.76
Human Site:
S1022
Identified Species:
28.89
UniProt:
Q9P2P5
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P2P5
NP_065811.1
1572
175769
S1022
D
P
R
L
P
L
Q
S
S
R
P
T
S
A
L
Chimpanzee
Pan troglodytes
XP_516001
1572
175733
S1022
D
P
R
L
P
L
Q
S
S
R
P
T
S
A
L
Rhesus Macaque
Macaca mulatta
XP_001096775
1606
179529
N1055
D
P
R
I
P
L
Q
N
G
R
L
P
N
H
L
Dog
Lupus familis
XP_850781
1366
151109
S857
L
L
A
R
P
G
H
S
L
V
A
A
I
R
S
Cat
Felis silvestris
Mouse
Mus musculus
Q6I6G8
1578
176216
S1028
D
P
R
L
P
L
Q
S
S
R
P
T
S
A
L
Rat
Rattus norvegicus
Q62940
887
102376
S378
V
T
S
S
N
H
S
S
R
G
G
S
S
Q
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507682
1657
184662
N1106
D
P
R
I
P
L
Q
N
G
R
L
P
N
H
L
Chicken
Gallus gallus
XP_421906
1566
176048
S1016
D
P
R
L
P
L
Q
S
S
R
P
T
S
A
L
Frog
Xenopus laevis
Q2TAS2
751
86306
M242
S
Q
R
H
R
N
Y
M
S
R
T
H
L
H
T
Zebra Danio
Brachydanio rerio
A9JRZ0
765
87445
G256
T
P
P
D
L
P
E
G
Y
E
Q
R
T
T
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVI3
1007
114856
P498
D
H
T
D
S
H
N
P
S
D
I
S
A
P
S
Honey Bee
Apis mellifera
XP_392900
1204
136801
R694
P
T
E
S
I
H
I
R
T
L
I
D
E
A
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39940
809
91798
T300
S
S
D
N
S
S
V
T
V
Q
V
G
G
G
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
56.7
52.7
N.A.
94.8
25.7
N.A.
53.3
86.7
24.2
23.9
N.A.
27.4
39.6
N.A.
N.A.
Protein Similarity:
100
99.6
68.1
62.8
N.A.
96.6
38
N.A.
64.9
91.5
34.5
34.4
N.A.
40
53.4
N.A.
N.A.
P-Site Identity:
100
100
53.3
13.3
N.A.
100
13.3
N.A.
53.3
100
20
6.6
N.A.
13.3
6.6
N.A.
N.A.
P-Site Similarity:
100
100
73.3
13.3
N.A.
100
20
N.A.
73.3
100
20
20
N.A.
26.6
13.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
36.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
0
0
0
0
8
8
8
39
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
54
0
8
16
0
0
0
0
0
8
0
8
0
0
0
% D
% Glu:
0
0
8
0
0
0
8
0
0
8
0
0
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
8
0
8
16
8
8
8
8
8
0
% G
% His:
0
8
0
8
0
24
8
0
0
0
0
8
0
24
0
% H
% Ile:
0
0
0
16
8
0
8
0
0
0
16
0
8
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
8
8
0
31
8
47
0
0
8
8
16
0
8
0
47
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
8
8
8
16
0
0
0
0
16
0
0
% N
% Pro:
8
54
8
0
54
8
0
8
0
0
31
16
0
8
8
% P
% Gln:
0
8
0
0
0
0
47
0
0
8
8
0
0
8
8
% Q
% Arg:
0
0
54
8
8
0
0
8
8
54
0
8
0
8
0
% R
% Ser:
16
8
8
16
16
8
8
47
47
0
0
16
39
0
24
% S
% Thr:
8
16
8
0
0
0
0
8
8
0
8
31
8
8
16
% T
% Val:
8
0
0
0
0
0
8
0
8
8
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _