KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HECW2
All Species:
20.91
Human Site:
S1163
Identified Species:
38.33
UniProt:
Q9P2P5
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P2P5
NP_065811.1
1572
175769
S1163
L
H
P
S
Y
C
Q
S
P
R
G
S
P
V
S
Chimpanzee
Pan troglodytes
XP_516001
1572
175733
S1163
L
H
P
S
Y
C
Q
S
P
R
G
S
P
V
S
Rhesus Macaque
Macaca mulatta
XP_001096775
1606
179529
S1197
F
H
P
G
Y
S
F
S
P
R
C
S
P
C
S
Dog
Lupus familis
XP_850781
1366
151109
E988
S
P
Y
R
R
D
F
E
A
K
L
R
N
F
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q6I6G8
1578
176216
S1169
L
H
P
S
Y
C
Q
S
P
R
G
S
P
V
S
Rat
Rattus norvegicus
Q62940
887
102376
K509
E
P
Y
S
R
D
Y
K
R
K
Y
E
F
F
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507682
1657
184662
S1248
F
H
P
G
Y
S
F
S
P
R
C
S
P
C
S
Chicken
Gallus gallus
XP_421906
1566
176048
S1157
L
H
P
S
Y
C
Q
S
P
R
G
S
P
V
S
Frog
Xenopus laevis
Q2TAS2
751
86306
R373
L
T
V
P
R
Y
K
R
D
L
V
H
K
L
K
Zebra Danio
Brachydanio rerio
A9JRZ0
765
87445
R387
L
T
V
P
K
Y
K
R
D
L
V
Q
K
L
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVI3
1007
114856
Y629
A
V
P
Y
S
R
D
Y
K
Q
K
Y
E
Y
F
Honey Bee
Apis mellifera
XP_392900
1204
136801
E825
A
P
Y
R
R
D
F
E
A
K
L
R
T
F
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39940
809
91798
Y431
L
D
Q
N
V
P
Q
Y
K
R
D
F
R
R
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
56.7
52.7
N.A.
94.8
25.7
N.A.
53.3
86.7
24.2
23.9
N.A.
27.4
39.6
N.A.
N.A.
Protein Similarity:
100
99.6
68.1
62.8
N.A.
96.6
38
N.A.
64.9
91.5
34.5
34.4
N.A.
40
53.4
N.A.
N.A.
P-Site Identity:
100
100
60
0
N.A.
100
6.6
N.A.
60
100
6.6
6.6
N.A.
6.6
0
N.A.
N.A.
P-Site Similarity:
100
100
60
6.6
N.A.
100
13.3
N.A.
60
100
20
20
N.A.
13.3
6.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
36.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
0
0
0
0
0
0
16
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
31
0
0
0
0
16
0
0
16
0
% C
% Asp:
0
8
0
0
0
24
8
0
16
0
8
0
0
0
0
% D
% Glu:
8
0
0
0
0
0
0
16
0
0
0
8
8
0
0
% E
% Phe:
16
0
0
0
0
0
31
0
0
0
0
8
8
24
8
% F
% Gly:
0
0
0
16
0
0
0
0
0
0
31
0
0
0
0
% G
% His:
0
47
0
0
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
8
0
16
8
16
24
8
0
16
0
24
% K
% Leu:
54
0
0
0
0
0
0
0
0
16
16
0
0
16
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
0
0
0
0
0
0
8
0
0
% N
% Pro:
0
24
54
16
0
8
0
0
47
0
0
0
47
0
0
% P
% Gln:
0
0
8
0
0
0
39
0
0
8
0
8
0
0
0
% Q
% Arg:
0
0
0
16
31
8
0
16
8
54
0
16
8
8
8
% R
% Ser:
8
0
0
39
8
16
0
47
0
0
0
47
0
0
47
% S
% Thr:
0
16
0
0
0
0
0
0
0
0
0
0
8
0
0
% T
% Val:
0
8
16
0
8
0
0
0
0
0
16
0
0
31
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
24
8
47
16
8
16
0
0
8
8
0
8
16
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _