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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HECW2 All Species: 10.3
Human Site: S800 Identified Species: 18.89
UniProt: Q9P2P5 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P2P5 NP_065811.1 1572 175769 S800 P S V R Q D V S R Y Q R V D E
Chimpanzee Pan troglodytes XP_516001 1572 175733 S800 P S V R Q D V S R Y Q R V D E
Rhesus Macaque Macaca mulatta XP_001096775 1606 179529 H822 P S L R P E H H H Y P T I D E
Dog Lupus familis XP_850781 1366 151109 Q664 P E E D S G N Q S C E Q V P G
Cat Felis silvestris
Mouse Mus musculus Q6I6G8 1578 176216 S806 P S V R Q D V S R Y Q R V D E
Rat Rattus norvegicus Q62940 887 102376 F185 R P Y T F K D F V L H P R S H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507682 1657 184662 H870 P S L R P D H H H Y P T I D E
Chicken Gallus gallus XP_421906 1566 176048 Y796 V R Q D V S R Y Q R V D E A L
Frog Xenopus laevis Q2TAS2 751 86306 S49 D G S G Q C H S T D T V K N T
Zebra Danio Brachydanio rerio A9JRZ0 765 87445 Q63 T L D P K W N Q H Y D L Y I G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VVI3 1007 114856 D305 R R F H I S V D D T E S G R S
Honey Bee Apis mellifera XP_392900 1204 136801 V501 R I D S H G R V F Y I D H I N
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P39940 809 91798 G107 E D T A T S S G R P R E E T I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 56.7 52.7 N.A. 94.8 25.7 N.A. 53.3 86.7 24.2 23.9 N.A. 27.4 39.6 N.A. N.A.
Protein Similarity: 100 99.6 68.1 62.8 N.A. 96.6 38 N.A. 64.9 91.5 34.5 34.4 N.A. 40 53.4 N.A. N.A.
P-Site Identity: 100 100 40 13.3 N.A. 100 0 N.A. 46.6 0 13.3 6.6 N.A. 6.6 6.6 N.A. N.A.
P-Site Similarity: 100 100 60 26.6 N.A. 100 0 N.A. 60 6.6 20 13.3 N.A. 13.3 6.6 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 26.7 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 36.7 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 0 0 0 0 0 0 0 0 0 8 0 % A
% Cys: 0 0 0 0 0 8 0 0 0 8 0 0 0 0 0 % C
% Asp: 8 8 16 16 0 31 8 8 8 8 8 16 0 39 0 % D
% Glu: 8 8 8 0 0 8 0 0 0 0 16 8 16 0 39 % E
% Phe: 0 0 8 0 8 0 0 8 8 0 0 0 0 0 0 % F
% Gly: 0 8 0 8 0 16 0 8 0 0 0 0 8 0 16 % G
% His: 0 0 0 8 8 0 24 16 24 0 8 0 8 0 8 % H
% Ile: 0 8 0 0 8 0 0 0 0 0 8 0 16 16 8 % I
% Lys: 0 0 0 0 8 8 0 0 0 0 0 0 8 0 0 % K
% Leu: 0 8 16 0 0 0 0 0 0 8 0 8 0 0 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 16 0 0 0 0 0 0 8 8 % N
% Pro: 47 8 0 8 16 0 0 0 0 8 16 8 0 8 0 % P
% Gln: 0 0 8 0 31 0 0 16 8 0 24 8 0 0 0 % Q
% Arg: 24 16 0 39 0 0 16 0 31 8 8 24 8 8 0 % R
% Ser: 0 39 8 8 8 24 8 31 8 0 0 8 0 8 8 % S
% Thr: 8 0 8 8 8 0 0 0 8 8 8 16 0 8 8 % T
% Val: 8 0 24 0 8 0 31 8 8 0 8 8 31 0 0 % V
% Trp: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 8 0 0 0 0 8 0 54 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _