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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HECW2
All Species:
10
Human Site:
S895
Identified Species:
18.33
UniProt:
Q9P2P5
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P2P5
NP_065811.1
1572
175769
S895
E
A
D
F
H
Q
A
S
A
D
F
R
R
E
N
Chimpanzee
Pan troglodytes
XP_516001
1572
175733
S895
E
A
D
F
H
Q
A
S
A
D
F
R
R
E
N
Rhesus Macaque
Macaca mulatta
XP_001096775
1606
179529
S928
S
E
A
E
S
S
Q
S
S
L
D
L
R
R
E
Dog
Lupus familis
XP_850781
1366
151109
N756
K
V
R
R
D
A
R
N
F
E
R
Y
Q
H
N
Cat
Felis silvestris
Mouse
Mus musculus
Q6I6G8
1578
176216
S901
E
A
D
F
H
Q
A
S
A
D
F
R
R
E
N
Rat
Rattus norvegicus
Q62940
887
102376
P277
R
T
T
Q
W
K
R
P
S
P
E
D
D
L
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507682
1657
184662
P979
L
E
A
D
S
S
Q
P
N
L
E
L
R
R
E
Chicken
Gallus gallus
XP_421906
1566
176048
N889
E
T
D
F
H
H
S
N
A
D
F
R
R
E
N
Frog
Xenopus laevis
Q2TAS2
751
86306
R141
V
S
L
Q
S
R
D
R
I
G
S
G
G
Q
V
Zebra Danio
Brachydanio rerio
A9JRZ0
765
87445
F155
V
V
D
C
S
R
L
F
D
N
D
L
P
D
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVI3
1007
114856
L397
P
E
I
S
A
T
S
L
Q
N
D
L
R
P
V
Honey Bee
Apis mellifera
XP_392900
1204
136801
L593
T
S
P
P
V
L
F
L
T
R
P
D
F
F
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39940
809
91798
A199
T
L
Q
S
G
T
T
A
A
T
N
T
A
T
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
56.7
52.7
N.A.
94.8
25.7
N.A.
53.3
86.7
24.2
23.9
N.A.
27.4
39.6
N.A.
N.A.
Protein Similarity:
100
99.6
68.1
62.8
N.A.
96.6
38
N.A.
64.9
91.5
34.5
34.4
N.A.
40
53.4
N.A.
N.A.
P-Site Identity:
100
100
13.3
6.6
N.A.
100
0
N.A.
6.6
73.3
0
6.6
N.A.
6.6
0
N.A.
N.A.
P-Site Similarity:
100
100
20
33.3
N.A.
100
13.3
N.A.
6.6
86.6
20
26.6
N.A.
20
6.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
36.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
24
16
0
8
8
24
8
39
0
0
0
8
0
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
39
8
8
0
8
0
8
31
24
16
8
8
0
% D
% Glu:
31
24
0
8
0
0
0
0
0
8
16
0
0
31
16
% E
% Phe:
0
0
0
31
0
0
8
8
8
0
31
0
8
8
0
% F
% Gly:
0
0
0
0
8
0
0
0
0
8
0
8
8
0
8
% G
% His:
0
0
0
0
31
8
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
0
8
0
0
0
0
0
8
0
0
0
0
0
0
% I
% Lys:
8
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% K
% Leu:
8
8
8
0
0
8
8
16
0
16
0
31
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
16
8
16
8
0
0
0
39
% N
% Pro:
8
0
8
8
0
0
0
16
0
8
8
0
8
8
0
% P
% Gln:
0
0
8
16
0
24
16
0
8
0
0
0
8
8
0
% Q
% Arg:
8
0
8
8
0
16
16
8
0
8
8
31
54
16
0
% R
% Ser:
8
16
0
16
31
16
16
31
16
0
8
0
0
0
0
% S
% Thr:
16
16
8
0
0
16
8
0
8
8
0
8
0
8
24
% T
% Val:
16
16
0
0
8
0
0
0
0
0
0
0
0
0
16
% V
% Trp:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _