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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HECW2
All Species:
4.24
Human Site:
T726
Identified Species:
7.78
UniProt:
Q9P2P5
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P2P5
NP_065811.1
1572
175769
T726
G
P
G
A
E
S
A
T
V
P
D
Q
E
E
L
Chimpanzee
Pan troglodytes
XP_516001
1572
175733
T726
G
P
G
A
E
S
A
T
V
P
D
Q
E
L
L
Rhesus Macaque
Macaca mulatta
XP_001096775
1606
179529
F746
E
E
E
E
N
S
A
F
E
S
V
P
D
S
M
Dog
Lupus familis
XP_850781
1366
151109
L591
Y
P
T
I
D
E
P
L
P
P
N
W
E
A
R
Cat
Felis silvestris
Mouse
Mus musculus
Q6I6G8
1578
176216
A726
G
S
A
A
E
A
A
A
L
S
E
Q
G
E
L
Rat
Rattus norvegicus
Q62940
887
102376
L112
Y
D
P
M
S
G
V
L
T
S
V
Q
T
K
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507682
1657
184662
F794
E
E
E
E
N
S
A
F
E
S
V
P
D
S
V
Chicken
Gallus gallus
XP_421906
1566
176048
G723
E
V
Q
E
A
E
G
G
E
L
Q
D
Q
E
D
Frog
Xenopus laevis
Q2TAS2
751
86306
Zebra Danio
Brachydanio rerio
A9JRZ0
765
87445
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVI3
1007
114856
E232
V
E
A
T
N
A
G
E
T
S
A
Q
P
H
P
Honey Bee
Apis mellifera
XP_392900
1204
136801
V428
N
S
K
S
R
R
A
V
T
K
S
I
A
L
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39940
809
91798
G34
F
A
V
L
T
I
D
G
Y
Q
T
K
S
T
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
56.7
52.7
N.A.
94.8
25.7
N.A.
53.3
86.7
24.2
23.9
N.A.
27.4
39.6
N.A.
N.A.
Protein Similarity:
100
99.6
68.1
62.8
N.A.
96.6
38
N.A.
64.9
91.5
34.5
34.4
N.A.
40
53.4
N.A.
N.A.
P-Site Identity:
100
93.3
13.3
20
N.A.
46.6
6.6
N.A.
13.3
6.6
0
0
N.A.
6.6
13.3
N.A.
N.A.
P-Site Similarity:
100
93.3
26.6
33.3
N.A.
66.6
13.3
N.A.
26.6
13.3
0
0
N.A.
13.3
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
36.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
16
24
8
16
47
8
0
0
8
0
8
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
8
0
8
0
0
0
16
8
16
0
8
% D
% Glu:
24
24
16
24
24
16
0
8
24
0
8
0
24
24
0
% E
% Phe:
8
0
0
0
0
0
0
16
0
0
0
0
0
0
0
% F
% Gly:
24
0
16
0
0
8
16
16
0
0
0
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
0
0
8
0
8
0
0
0
0
0
8
0
0
0
% I
% Lys:
0
0
8
0
0
0
0
0
0
8
0
8
0
8
0
% K
% Leu:
0
0
0
8
0
0
0
16
8
8
0
0
0
16
31
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
8
0
0
0
24
0
0
0
0
0
8
0
0
0
0
% N
% Pro:
0
24
8
0
0
0
8
0
8
24
0
16
8
0
8
% P
% Gln:
0
0
8
0
0
0
0
0
0
8
8
39
8
0
0
% Q
% Arg:
0
0
0
0
8
8
0
0
0
0
0
0
0
0
8
% R
% Ser:
0
16
0
8
8
31
0
0
0
39
8
0
8
16
8
% S
% Thr:
0
0
8
8
8
0
0
16
24
0
8
0
8
8
8
% T
% Val:
8
8
8
0
0
0
8
8
16
0
24
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
16
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _