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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HECW2
All Species:
13.94
Human Site:
Y419
Identified Species:
25.56
UniProt:
Q9P2P5
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P2P5
NP_065811.1
1572
175769
Y419
R
Q
D
S
L
N
D
Y
L
D
A
I
E
H
N
Chimpanzee
Pan troglodytes
XP_516001
1572
175733
Y419
R
Q
D
S
L
N
D
Y
L
D
A
I
E
H
N
Rhesus Macaque
Macaca mulatta
XP_001096775
1606
179529
G439
S
V
G
P
E
G
A
G
D
L
L
A
Q
V
Q
Dog
Lupus familis
XP_850781
1366
151109
L288
A
E
E
L
A
E
R
L
E
L
G
G
E
A
P
Cat
Felis silvestris
Mouse
Mus musculus
Q6I6G8
1578
176216
Y418
R
Q
D
S
L
N
D
Y
L
D
A
I
E
H
N
Rat
Rattus norvegicus
Q62940
887
102376
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507682
1657
184662
V485
V
V
E
P
V
D
A
V
D
P
T
E
P
S
P
Chicken
Gallus gallus
XP_421906
1566
176048
Y420
R
Q
D
S
L
N
D
Y
L
D
A
I
E
H
N
Frog
Xenopus laevis
Q2TAS2
751
86306
Zebra Danio
Brachydanio rerio
A9JRZ0
765
87445
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVI3
1007
114856
Honey Bee
Apis mellifera
XP_392900
1204
136801
S125
V
L
P
P
E
Y
S
S
S
G
K
I
N
S
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39940
809
91798
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
56.7
52.7
N.A.
94.8
25.7
N.A.
53.3
86.7
24.2
23.9
N.A.
27.4
39.6
N.A.
N.A.
Protein Similarity:
100
99.6
68.1
62.8
N.A.
96.6
38
N.A.
64.9
91.5
34.5
34.4
N.A.
40
53.4
N.A.
N.A.
P-Site Identity:
100
100
0
6.6
N.A.
100
0
N.A.
0
100
0
0
N.A.
0
6.6
N.A.
N.A.
P-Site Similarity:
100
100
6.6
20
N.A.
100
0
N.A.
20
100
0
0
N.A.
0
6.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
36.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
8
0
16
0
0
0
31
8
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
31
0
0
8
31
0
16
31
0
0
0
0
0
% D
% Glu:
0
8
16
0
16
8
0
0
8
0
0
8
39
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
0
0
8
0
0
8
0
8
0
8
8
8
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
31
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
39
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% K
% Leu:
0
8
0
8
31
0
0
8
31
16
8
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
31
0
0
0
0
0
0
8
0
31
% N
% Pro:
0
0
8
24
0
0
0
0
0
8
0
0
8
0
16
% P
% Gln:
0
31
0
0
0
0
0
0
0
0
0
0
8
0
8
% Q
% Arg:
31
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% R
% Ser:
8
0
0
31
0
0
8
8
8
0
0
0
0
16
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% T
% Val:
16
16
0
0
8
0
0
8
0
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
31
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _